Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 18/20 | 0.55 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201393 | 0.85 | ABCG2 (0.55) | ABCG2 | |
| SCHEMBL22201341 | 0.84 | PRKD1 (0.66) | ABCG2PRKD1 | |
| SCHEMBL22201394 | 0.83 | FGFR2 (0.54) | ABCG2FGFR2FLT3PRKD1 | |
| SCHEMBL22201252 | 0.83 | PRKD1 (0.47) | ABCG2FGFR2FLT3PRKD1 | |
| SCHEMBL22201259 | 0.83 | ABCG2 (0.51) | ABCG2 | |
| SCHEMBL22201408 | 0.82 | ABCG2 (0.53) | ABCG2 | |
| SCHEMBL22201422 | 0.82 | ABCG2 (0.60) | ABCG2 | |
| SCHEMBL22201358 | 0.81 | TGFBR1 (0.53) | ABCG2FGFR2FLT3PRKD1 | |
| SCHEMBL22201469 | 0.80 | FGFR2 (0.62) | FGFR2FLT3PRKD1 | |
| SCHEMBL22201395 | 0.80 | FGFR2 (0.55) | ABCG2FGFR2FLT3PRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |