Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.80 |
| ▸ | LMNA | P02545 | 4/20 | 0.80 |
| ▸ | HPGD | P15428 | 4/20 | 0.80 |
| ▸ | MEN1 | O00255 | 4/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.80 |
| ▸ | TP53 | P04637 | 2/20 | 0.80 |
| ▸ | MAPT | P10636 | 2/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.80 |
| ▸ | USP2 | O75604 | 2/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001170 | 0.90 | LMNA (0.77) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL22201433 | 0.89 | ALDH1A1 (0.63) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL12316850 | 0.88 | MEN1 (0.73) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL9937633 | 0.86 | ABCG2 (0.74) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL2293460 | 0.84 | MEN1 (0.69) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL22201270 | 0.84 | MEN1 (0.61) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL6001380 | 0.82 | PDE5A (0.67) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL22201343 | 0.82 | HPGD (0.65) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL22201610 | 0.82 | HPGD (0.59) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL2294663 | 0.81 | KDM1A (0.66) | ALDH1A1LMNAHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |