Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 1/20 | 0.62 |
| ▸ | FLT3 | P36888 | 1/20 | 0.62 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.53 |
| ▸ | PRKCH | P24723 | 1/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 7/20 | 0.46 |
| ▸ | FLT1 | P17948 | 7/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201257 | 0.85 | FGFR2 (0.62) | FGFR2FLT3PRKD1PRKCHPRKCE | |
| SCHEMBL22201475 | 0.83 | PRKCH (0.47) | FGFR2FLT3PRKD1PRKCHPRKCE | |
| SCHEMBL22201476 | 0.82 | PRKCH (0.52) | FGFR2FLT3PRKCHPRKCESYK | |
| SCHEMBL22201381 | 0.82 | PRKCH (0.51) | FGFR2FLT3PRKCHPRKCETGFBR1 | |
| SCHEMBL22201449 | 0.82 | PRKCH (0.51) | FGFR2FLT3PRKCHPRKCEGRM4 | |
| SCHEMBL22201452 | 0.82 | PRKCH (0.58) | PRKCHPRKCETGFBR1SYKLMNA | |
| SCHEMBL22201598 | 0.81 | FGFR2 (0.65) | FGFR2FLT3PRKD1PRKCHPRKCE | |
| SCHEMBL22201640 | 0.80 | PRKCH (0.52) | FGFR2FLT3PRKCHPRKCEEGFR | |
| SCHEMBL22803770 | 0.80 | EGFR (0.58) | FGFR2FLT3PRKD1TGFBR1EGFR | |
| SCHEMBL30302532 | 0.80 | EGFR (0.58) | FGFR2FLT3PRKD1TGFBR1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |