Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCH | P24723 | 1/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.46 |
| ▸ | MTOR | P42345 | 3/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 7/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201639 | 0.85 | PRKCH (0.52) | PRKCHPRKCEEGFRKDM4ESYK | |
| SCHEMBL22201469 | 0.80 | FGFR2 (0.62) | PRKCHPRKCEEGFRKDRSYK | |
| SCHEMBL22201545 | 0.79 | KDM4E (0.72) | KDM4E | |
| SCHEMBL1640966 | 0.78 | FGFR2 (0.61) | RETPIK3CAPIK3CDMTORPIK3CB | |
| SCHEMBL22201476 | 0.74 | PRKCH (0.52) | PRKCHPRKCESYKFGFR2FLT3 | |
| SCHEMBL22201369 | 0.74 | LMNA (0.63) | PRKCHPRKCEEGFRKDM4ESYK | |
| SCHEMBL22201452 | 0.72 | PRKCH (0.58) | PRKCHPRKCEKDM4ESYK | |
| SCHEMBL22201636 | 0.72 | PRKCH (0.47) | PRKCHPRKCESYK | |
| SCHEMBL22201450 | 0.71 | PRKCH (0.51) | PRKCHPRKCERETEGFRKDR | |
| SCHEMBL22201381 | 0.71 | PRKCH (0.51) | PRKCHPRKCESYKFGFR2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |