Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCH | P24723 | 1/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 14/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201469 | 0.82 | FGFR2 (0.62) | PRKCHPRKCESYKLMNAHPGD | |
| SCHEMBL22201408 | 0.82 | ABCG2 (0.53) | LMNAHPGDMAPTALDH1A1POLB | |
| SCHEMBL22201627 | 0.81 | HPGD (0.67) | LMNAHPGDMAPTALDH1A1POLB | |
| SCHEMBL22201639 | 0.80 | PRKCH (0.52) | PRKCHPRKCESYKLMNA | |
| SCHEMBL22201369 | 0.78 | LMNA (0.63) | PRKCHPRKCESYKLMNAHPGD | |
| SCHEMBL22201466 | 0.76 | LMNA (0.49) | LMNAHPGDMAPTALDH1A1POLB | |
| SCHEMBL22201625 | 0.75 | LMNA (0.47) | LMNAHPGDMAPTALDH1A1POLB | |
| SCHEMBL22201452 | 0.74 | PRKCH (0.58) | PRKCHPRKCESYKLMNAHPGD | |
| SCHEMBL22201429 | 0.74 | ABCG2 (0.42) | — | |
| SCHEMBL22201640 | 0.74 | PRKCH (0.52) | PRKCHPRKCESYKFGFR2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |