Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | GLA | P06280 | 4/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31703846 | 0.87 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTNPC1RAB9AGAA | |
| SCHEMBL16112694 | 0.79 | RAB9A (0.50) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL1743131 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTNPC1RAB9AGAA | |
| SCHEMBL1743128 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTNPC1RAB9AGAA | |
| SCHEMBL1746197 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTNPC1RAB9AGAA | |
| SCHEMBL30317989 | 0.76 | CYP1A2 (0.58) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL28991026 | 0.76 | CYP1A2 (0.58) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL3851706 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTNPC1RAB9AGAA | |
| SCHEMBL8304295 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTNPC1RAB9AGAA | |
| SCHEMBL25113833 | 0.74 | LMNA (0.56) | SMN1; SMN2MAPTNPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |