Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCH | P24723 | 1/20 | 0.48 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | BUB1 | O43683 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201268 | 0.91 | TGFBR1 (0.51) | PRKCHPRKCEGRM4MKNK1TGFBR1 | |
| SCHEMBL22201450 | 0.86 | PRKCH (0.51) | PRKCHPRKCEGRM4SYKMAPT | |
| SCHEMBL22201442 | 0.81 | HPGD (0.64) | MAPTKDM4EKMT2ATGFBR1ALDH1A1 | |
| SCHEMBL22201257 | 0.78 | FGFR2 (0.62) | PRKCHPRKCEGRM4SYKMAPT | |
| SCHEMBL22201285 | 0.78 | ABCG2 (0.55) | — | |
| SCHEMBL16941497 | 0.77 | HPGD (0.65) | PRKCHPRKCEMAPTKDM4ETGFBR1 | |
| SCHEMBL22201282 | 0.76 | HPGD (0.64) | PRKCHPRKCEMAPTKDM4EKMT2A | |
| SCHEMBL22201296 | 0.75 | LATS1 (0.52) | MAPTKDM4ECDC7TGFBR1ALDH1A1 | |
| SCHEMBL14514008 | 0.74 | BUB1 (0.49) | SYKMAPTKDM4ERAB9ANPC1 | |
| SCHEMBL13955582 | 0.73 | KDR (0.44) | GRM4SYKMAPTKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |