SCHEMBL2220176

SCHEMBL2220176

COc1ccc(SOSc2ccc(OC)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
CA7 P43166 2/20 0.58
CA9 Q16790 2/20 0.58
CA12 O43570 1/20 0.58
CA14 Q9ULX7 1/20 0.58
CYP1A1 P04798 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP1B1 Q16678 1/20 0.48
ACHE P22303 1/20 0.48
TDP1 Q9NUW8 3/20 0.46
MAPK1 P28482 2/20 0.46
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
THRB P10828 1/20 0.44
RECQL P46063 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8763072 0.91 CA4 (0.54) CA1CA2CA7CA9CA12
SCHEMBL2472483 0.84 CA1 (0.58) CA1CA2CA7CA9CA12
Hydrogen Sulfide SCHEMBL17008163 0.82 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL116400 0.79 CA1 (0.58) CA1CA2CA7CA9CA12
SCHEMBL438406 0.78 CA1 (0.65) CA1CA2CA7CA9CA12
SCHEMBL482369 0.78 CA1 (0.65) CA1CA2CA7CA9CA12
SCHEMBL9544764 0.77 CA1 (0.48) CA1CA2CA7CA9CA12
SCHEMBL12155240 0.77 CA1 (0.48) CA1CA2CA7CA9CA12
SCHEMBL14588715 0.77 CA1 (0.48) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL8489 0.76 CA1 (1.00) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371674-A Preparation method of donor-acceptor type metal organic framework photocatalyst and application of photocatalytic amine oxide/thioether 长沙理工大学 2025-01-28 CN claimed
CN-115197179-A Method for preparing thioether and disulfide through C-S bond double decomposition reaction without participation of transition metal 常州大学 2022-10-18 CN claimed
CN-117619447-A PHI/zinc oxide heterojunction photocatalyst and low-temperature synthesis method and application thereof 大连理工大学 2024-03-01 CN disclosed
CN-117486662-A Method for synthesizing sulfoxide compound by heterogeneous catalysis 成都理工大学 2024-02-02 CN disclosed
CN-115197179-B Method for preparing thioether and disulfide through C-S bond double decomposition reaction without participation of transition metal 常州大学 2023-08-22 CN disclosed
CN-113518805-B Photoinitiator 意大利艾坚蒙树脂有限公司 2023-08-08 CN disclosed
CN-110540525-B Synthetic method of 3-thioether-group quinoxalinone compound 广西师范大学 2022-11-22 CN disclosed
CN-115197179-A Method for preparing thioether and disulfide through C-S bond double decomposition reaction without participation of transition metal 常州大学 2022-10-18 CN disclosed
CN-111875523-B Synthetic method of alpha-fluorovinyl thioether derivative 温州大学 2022-03-25 CN disclosed
CN-111285860-B Indole derivatives containing disulfanyl heterocyclic structure or stereoisomer thereof, or salt or solvate thereof 贵州大学 2021-08-10 CN disclosed
CN-110105255-B Mild synthesis method of diaryl thioether 江西理工大学 2020-11-03 CN disclosed
US-20110178138-A1 INHIBITORS OF PROTEIN PRENYLTRANSFERASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-07-21 US disclosed
CN-101029937-B Optical film, anti-reflection film, polarizing plate and image display device FUJI PHOTO FILM CO LTD 2011-06-22 CN disclosed
CN-101052685-B Cured composition, antireflection film and method for producing the same, polarizing plate, and image display device FUJI PHOTO FILM CO LTD 2011-05-04 CN disclosed
CN-101296731-A Novel benzopyran derivatives as potassium channel openers JANSSEN PHARMACEUTICA NV (BE) 2008-10-29 CN disclosed
CN-101052685-A Cured composition, antireflection film and method for producing the same, polarizing plate, and image display device FUJIFILM CORP (JP) 2007-10-10 CN disclosed
CN-101029937-A Optical film, anti-reflection film, polarizing plate and image display device FUJIFILM CORP (JP) 2007-09-05 CN disclosed
EP-1570312-A4 LIQUID CRYSTAL DISPLAY OF OCB OR VA MODE FUJIFILM CORP (JP) 2007-05-09 EP disclosed
EP-1570312-A1 LIQUID CRYSTAL DISPLAY OF OCB OR VA MODE FUJI PHOTO FILM CO., LTD. (JP) 2005-09-07 EP disclosed
WO-2004055584-A1 LIQUID CRYSTAL DISPLAY OF OCB OR VA MODE FUJI PHOTO FILM CO., LTD. (JP) 2004-07-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110178138-A1 INHIBITORS OF PROTEIN PRENYLTRANSFERASES RABGGTA, FNTA, RABGGTB CA1 4738/4885CA2 4616/4885CA7 4205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.