SCHEMBL482369

SCHEMBL482369

COc1ccc(Sc2ccc(OC)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA12 O43570 1/20 0.65
CA14 Q9ULX7 1/20 0.65
PTGIR P43119 6/20 0.63
HAO1 Q9UJM8 1/20 0.53
ACHE P22303 1/20 0.52
CYP1A1 P04798 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP1B1 Q16678 1/20 0.52
TDP1 Q9NUW8 3/20 0.50
MAPK1 P28482 2/20 0.50
KDM4E B2RXH2 1/20 0.48
NPC1 O15118 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
THRB P10828 1/20 0.48
RECQL P46063 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11848856 0.97 CA1 (0.61) CA1CA2CA7CA9CA12
SCHEMBL3484650 0.90 ACHE (0.71) CA1CA2CA7CA9CA12
SCHEMBL2272158 0.90 CA4 (0.59) CA1CA2CA7CA9CA12
SCHEMBL4743804 0.88 HPGD (0.53) CA1CA2CA7CA9CA12
SCHEMBL7929122 0.88 NFE2L2 (0.57) CA1CA2CA7CA9CA12
SCHEMBL3414374 0.88 LTA4H (0.64) CA1CA2CA7CA9CA12
SCHEMBL5786907 0.88 TDP1 (0.73) CA1CA2CA7CA9CA12
SCHEMBL21763722 0.88 APP (0.61) CA1CA2CA7CA9CA12
SCHEMBL20751758 0.88 PTGIR (0.53) CA1CA2CA7CA9CA12
SCHEMBL7285896 0.86 DDAH1 (0.61) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011992-A UV-curing-delaying packaging adhesive for OLED display panel, OLED display panel and manufacturing method of OLED display panel 惠州硕贝德半导体材料有限公司 2026-05-12 CN claimed
CN-119780333-A Method for testing water content of organic peroxide and application thereof 江苏扬农化工集团有限公司 2025-04-08 CN claimed
CN-115197179-B Method for preparing thioether and disulfide through C-S bond double decomposition reaction without participation of transition metal 常州大学 2023-08-22 CN claimed
CN-115141814-B Application of 4-hydroxyacetophenone monooxygenase 江南大学 2023-05-05 CN claimed
CN-115197179-A Method for preparing thioether and disulfide through C-S bond double decomposition reaction without participation of transition metal 常州大学 2022-10-18 CN claimed
CN-106278965-A Aryl alkyl asymmetric over cure compounds and synthetic method thereof and application 华东师范大学 2017-01-04 CN claimed
US-4393241-A Synthesis of alkoxy and phenoxy substituted aryl sulfides CELANESE CORPORATION (US) 1983-07-12 US claimed
US-4089904-A OXIDATION OF SULFIDES AND SULFOXIDES, AQUEOUS SLURRY, MOLYBDIC ACID-PEROXIDE CATALYST CROWN ZELLERBACH CORPORATION (US) 1978-05-16 US claimed
CN-122011992-A UV-curing-delaying packaging adhesive for OLED display panel, OLED display panel and manufacturing method of OLED display panel 惠州硕贝德半导体材料有限公司 2026-05-12 CN disclosed
US-20250289852-A1 ANTIFUNGAL AGENTS AND USES THEREOF NAPP PHARMACEUTICAL GROUP LTD (GB) 2025-09-18 US disclosed
US-12344680-B2 Antifungal agents and uses thereof NAPP PHARMACEUTICAL GROUP LIMITED (GB) 2025-07-01 US disclosed
CN-120040472-A Method for synthesizing arylthiopyrano [3,2-e ] [1,2] oxazine compound through photocatalysis 南京工业大学 2025-05-27 CN disclosed
CN-116283684-B Green preparation method of diphenyl sulfide and derivative thereof 常州大学 2025-04-08 CN disclosed
CN-119780333-A Method for testing water content of organic peroxide and application thereof 江苏扬农化工集团有限公司 2025-04-08 CN disclosed
US-4393241-A Synthesis of alkoxy and phenoxy substituted aryl sulfides CELANESE CORPORATION (US) 1983-07-12 US disclosed
US-4339611-A BUTANOL, BUTANAL, COBALT, IODINE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-07-13 US disclosed
US-4251521-A HYPOGLYCEMIC AGENTS SANDOZ, INC. (US) 1981-02-17 US disclosed
US-4124370-A Diphenyl ethers for tobacco sucker control ROHM AND HAAS COMPANY (US) 1978-11-07 US disclosed
US-4089904-A OXIDATION OF SULFIDES AND SULFOXIDES, AQUEOUS SLURRY, MOLYBDIC ACID-PEROXIDE CATALYST CROWN ZELLERBACH CORPORATION (US) 1978-05-16 US disclosed
US-3988467-A Aminoacyl compounds CIBA-GEIGY CORPORATION (US) 1976-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344680-B2 Antifungal agents and uses thereof DPM1, ERG28, CYP51A1 CA1 4563/4885CA2 3411/4885CA7 1640/4885
US-20250289852-A1 ANTIFUNGAL AGENTS AND USES THEREOF DPM1, ERG28, CYP51A1 CA1 4563/4885CA2 3411/4885CA7 1640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.