SCHEMBL438406

SCHEMBL438406

COc1ccc(SSc2ccc(OC)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA12 O43570 1/20 0.65
CA14 Q9ULX7 1/20 0.65
FBP1 P09467 1/20 0.57
ACHE P22303 1/20 0.52
CYP1A1 P04798 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP1B1 Q16678 1/20 0.52
TDP1 Q9NUW8 3/20 0.50
MAPK1 P28482 2/20 0.50
ALDH1A1 P00352 3/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
KDM4E B2RXH2 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
THRB P10828 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12708273 0.90 ACHE (0.71) CA1CA2CA7CA9CA12
SCHEMBL9018822 0.90 CA4 (0.59) CA1CA2CA7CA9CA12
SCHEMBL4270701 0.89 CA1 (0.58) CA1CA2CA7CA9CA12
SCHEMBL11021872 0.89 CA1 (0.58) CA1CA2CA7CA9CA12
SCHEMBL17052772 0.88 TDP1 (0.73) CA1CA2CA7CA9CA12
SCHEMBL26193671 0.88 LTA4H (0.64) CA1CA2CA7CA9CA12
SCHEMBL10948006 0.87 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL19888533 0.82 ALDH1A1 (0.76) CA1CA2CA7CA9CA12
SCHEMBL12589778 0.82 APP (0.47) CA1CA2CA7CA9CA12
SCHEMBL482369 0.82 CA1 (0.65) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 445 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163101-A1 METHOD FOR INCREASING PRODUCTION YIELD OF ANTIBODY-DRUG CONJUGATE BY USING THIOL-REACTIVE ADDITIVE Research & Business Foundation Sungkyunkwan University (KR) 2025-05-22 US claimed
EP-4488290-A1 METHOD FOR INCREASING PRODUCTION YIELD OF ANTIBODY-DRUG CONJUGATE BY USING THIOL-REACTIVE ADDITIVE ABTIS Co., Ltd. (KR) 2025-01-08 EP claimed
WO-2024257830-A1 METHOD FOR PRODUCING AZULENE AND RELATED COMPOUNDS アルプス薬品工業株式会社 2024-12-19 WO claimed
CN-118026909-B Preparation method of 3, 3-diaryl indolenine series compounds 江西师范大学 2024-06-21 CN claimed
CN-118026909-A Preparation method of 3, 3-diaryl indolenine series compounds 江西师范大学 2024-05-14 CN claimed
CN-117945964-A Synthesis method of aryl alkyl asymmetric thioether 中国人民解放军军事科学院防化研究院 2024-04-30 CN claimed
WO-2023167564-A1 METHOD FOR INCREASING PRODUCTION YIELD OF ANTIBODY-DRUG CONJUGATE BY USING THIOL-REACTIVE ADDITIVE 앱티스 주식회사 2023-09-07 WO claimed
CN-116704872-A Preparation method of surface-enhanced Raman label 南京工业大学 2023-09-05 CN claimed
CN-115197179-B Method for preparing thioether and disulfide through C-S bond double decomposition reaction without participation of transition metal 常州大学 2023-08-22 CN claimed
CN-111052485-B Non-aqueous electrolyte for lithium secondary battery and lithium secondary battery comprising the same 株式会社LG新能源 2023-04-14 CN claimed
US-20150083466-A1 Method For The Functionalisation Of Metal Nanowires And The Production Of Electrodes COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-03-26 US claimed
US-20130330607-A1 ELECTROLYTIC SOLUTION AND LITHIUM-ION SECONDARY BATTERY KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2013-12-12 US claimed
EP-1304758-B1 NON-AQUEOUS ELECTROLYTE AND NON-AQUEOUS ELECTROLYTE SECONDARY CELL PANASONIC CORP (JP) 2009-05-27 EP claimed
EP-1199766-B1 Non-aqueous secondary battery having enhanced discharge capacity retention UBE INDUSTRIES (JP) 2008-05-28 EP claimed
US-7132199-B2 Non-aqueous electrolyte and non-aqueous electrolyte secondary battery MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2006-11-07 US claimed
US-6866966-B2 Efficiency UBE INDUSTRIES, LTD. (JP) 2005-03-15 US claimed
US-20040091786-A1 Non-aqueous electrolyte and non-aqueous electrolyte secondary cell MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2004-05-13 US claimed
EP-1304758-A1 NON-AQUEOUS ELECTROLYTE AND NON-AQUEOUS ELECTROLYTE SECONDARY CELL MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2003-04-23 EP claimed
US-20020122988-A1 Efficiency UBE INDUSTRIES, LTD. (JP) 2002-09-05 US claimed
EP-1199766-A2 Non-aqueous secondary battery having enhanced discharge capacity retention Ube Industries, Ltd. (JP) 2002-04-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163101-A1 METHOD FOR INCREASING PRODUCTION YIELD OF ANTIBODY-DRUG CONJUGATE BY USING THIOL-REACTIVE ADDITIVE TST, DHFR, FCGRT CA1 955/4885CA2 1903/4885CA7 1155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.