SCHEMBL22203151

SCHEMBL22203151

c1ccc(-c2ccc(-c3nc(-c4ccc(-c5ccccc5)cc4)nc(-n4c5ccc(-n6c7ccccc7c7c8ccccc8ccc76)cc5c5c6ccccc6ccc54)n3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.33
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAPT P10636 3/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
RECQL P46063 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KMT2A Q03164 3/20 0.32
MEN1 O00255 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
PTGES O14684 2/20 0.32
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32
TUBA3C P0DPH7 1/20 0.32
TUBA1B P68363 1/20 0.32
TUBA4A P68366 1/20 0.32
TUBB4B P68371 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25910624 0.98 ATM (0.36) ATMKDM4EL3MBTL1MAPTNPC1
SCHEMBL25910626 0.98 ATM (0.36) ATMKDM4EL3MBTL1MAPTNPC1
SCHEMBL25910615 0.98 ATM (0.36) ATMKDM4EL3MBTL1MAPTNPC1
SCHEMBL25910618 0.98 ATM (0.36) ATMKDM4EL3MBTL1MAPTNPC1
SCHEMBL24677468 0.95 KDM4E (0.38) ATMKDM4EL3MBTL1MAPTNPC1
SCHEMBL24677385 0.94 KDM4E (0.37) ATMKDM4EL3MBTL1MAPTNPC1
SCHEMBL22203154 0.94 ATM (0.37) ATMKDM4EL3MBTL1MAPTNPC1
SCHEMBL22883967 0.93 PTGES (0.32) ATMKDM4EL3MBTL1MAPTNPC1
SCHEMBL25910621 0.93 KDM4E (0.33) ATMKDM4EL3MBTL1MAPTNPC1
SCHEMBL25910263 0.93 ATM (0.35) ATMKDM4EL3MBTL1MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3677580-B1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEMICAL LTD (KR) 2021-09-22 EP disclosed
US-20210013425-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2021-01-14 US disclosed
EP-3677580-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2020-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210013425-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME CRY1, NR2E3, CRY2 ATM 1312/4885KDM4E 3835/4885L3MBTL1 1341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.