Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17199290 | 0.92 | HTT (0.43) | HTTNPC1RAB9AL3MBTL1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL17187687 | 0.88 | POLB (0.45) | HTTNPC1RAB9AL3MBTL1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL17187694 | 0.85 | MEN1 (0.38) | HTTNPC1RAB9AL3MBTL1CYP1A2 | |
| SCHEMBL17199107 | 0.84 | HDAC3 (0.48) | HTTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL17199293 | 0.79 | CYP1A2 (0.54) | CYP1A2MAPTCYP2C19POLBALDH1A1 | |
| SCHEMBL17187688 | 0.79 | POLB (0.52) | HTTL3MBTL1CYP1A2CYP2C19POLB | |
| SCHEMBL19220498 | 0.79 | MAPK1 (0.41) | HTTNPC1RAB9AL3MBTL1CYP1A2 | |
| SCHEMBL29473405 | 0.79 | POLB (0.52) | HTTL3MBTL1CYP1A2CYP2C19POLB | |
| Trifluoroacetic Acid SCHEMBL17187693 | 0.79 | MMP2 (0.40) | HTTNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL17199212 | 0.78 | HTT (0.55) | HTTL3MBTL1CYP1A2MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131882-B1 | PHENAZINIUM MEDIATORS | ROCHE DIAGNOSTICS GMBH (DE) | 2020-07-15 | — | — | EP | disclosed |