Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17199220 | 0.89 | GLO1 (0.47) | MMP2GLO1ALOX15HTTKMT2A | |
| Trifluoroacetic Acid SCHEMBL17187694 | 0.85 | MEN1 (0.38) | ALOX15HTTKMT2AMEN1NPC1 | |
| Trifluoroacetic Acid SCHEMBL17187687 | 0.81 | POLB (0.45) | HTTKMT2AMEN1NPC1USP2 | |
| Trifluoroacetic Acid SCHEMBL22203993 | 0.79 | HTT (0.38) | HTTKMT2AMEN1NPC1USP2 | |
| SCHEMBL12377714 | 0.74 | MEN1 (0.43) | ALOX15HTTKMT2AMEN1NPC1 | |
| Trifluoroacetic Acid SCHEMBL11902973 | 0.72 | LTB4R (0.37) | KMT2AMEN1NPC1USP2POLB | |
| Trifluoromethanesulfonic Acid SCHEMBL15268656 | 0.71 | MEN1 (0.51) | KMT2AMEN1NPC1USP2POLB | |
| SCHEMBL17199107 | 0.71 | HDAC3 (0.48) | HTTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL17199293 | 0.70 | CYP1A2 (0.54) | POLBALDH1A1 | |
| SCHEMBL17187688 | 0.70 | POLB (0.52) | HTTPOLBL3MBTL1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131882-A1 | PHENAZINIUM MEDIATORS | Roche Diagnostics GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |
| WO-2015158645-A1 | PHENAZINIUM MEDIATORS | ROCHE DIAGNOSTICS GMBH (DE) | 2015-10-22 | — | — | WO | disclosed |