Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.34 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19932639 | 0.84 | KMT2A (0.43) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30971062 | 0.81 | LMNA (0.39) | RXFP1MCL1ALOX15TSHRHIF1A | |
| SCHEMBL23800550 | 0.76 | RXFP1 (0.41) | RXFP1ALOX15TSHRKDM4EALDH1A1 | |
| SCHEMBL31268119 | 0.75 | KCNN3 (0.35) | TSHRKDM4EALDH1A1GLA | |
| SCHEMBL23104589 | 0.75 | KCNN3 (0.35) | TSHRKDM4EALDH1A1GLA | |
| SCHEMBL23809379 | 0.75 | NOTUM (0.38) | NOTUMALOX15TSHRCAMKK1CAMKK2 | |
| SCHEMBL21439147 | 0.74 | L3MBTL1 (0.46) | RXFP1 | |
| SCHEMBL30503520 | 0.73 | HRH4 (0.34) | — | |
| SCHEMBL26105826 | 0.73 | HRH4 (0.34) | — | |
| SCHEMBL19932596 | 0.72 | CHRM1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507289-B1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LTD (IN) | 2020-07-15 | — | — | EP | disclosed |