SCHEMBL22205129

SCHEMBL22205129

CCO[Si](CCn1cnnn1)(OCC)OCC

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
TP53 P04637 4/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.35
LMNA P02545 1/20 0.35
STAT5B P51692 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
LTA4H P09960 1/20 0.32
THRB P10828 2/20 0.32
RAB9A P51151 1/20 0.32
HRH3 Q9Y5N1 1/20 0.31
LTB4R Q15722 1/20 0.30
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22205100 0.89 MEN1 (0.52) ALDH1A1MEN1KMT2ATP53GAA
SCHEMBL22205196 0.87 MEN1 (0.50) ALDH1A1MEN1KMT2ATP53GAA
SCHEMBL22205160 0.86 MEN1 (0.48) ALDH1A1MEN1KMT2ATP53GAA
SCHEMBL22205122 0.86 MEN1 (0.48) ALDH1A1MEN1KMT2ATP53GAA
SCHEMBL22205133 0.86 MEN1 (0.48) ALDH1A1MEN1KMT2ATP53GAA
SCHEMBL22205202 0.86 MEN1 (0.48) ALDH1A1MEN1KMT2ATP53GAA
SCHEMBL22205127 0.86 MEN1 (0.48) ALDH1A1MEN1KMT2ATP53GAA
SCHEMBL2380409 0.80 MEN1 (0.48) ALDH1A1MEN1KMT2ATP53GAA
SCHEMBL21111119 0.73 ALDH1A1 (1.00) ALDH1A1MEN1KMT2ATP53GAA
SCHEMBL3643462 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111108111-B Tetrazole silane compound, method for synthesizing the compound, and use thereof 四国化成工业株式会社 2023-05-02 CN disclosed
US-11472823-B2 Tetrazole silane compound, method for synthesizing said compound and use thereof SHIKOKU CHEMICALS CORPORATION (JP) 2022-10-18 US disclosed
US-20210179642-A1 TETRAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2021-06-17 US disclosed
US-11014946-B2 Tetrazole silane compound, method for synthesizing said compound and use thereof SHIKOKU CHEMICALS CORPORATION (JP) 2021-05-25 US disclosed
US-10975108-B2 2021-04-13 US disclosed
EP-3686207-A1 TETRAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF Shikoku Chemicals Corporation (JP) 2020-07-29 EP disclosed
US-20200223875-A1 TETRAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2020-07-16 US disclosed
CN-111108111-A Tetrazolylsilane compound, method for synthesizing same, and use thereof 四国化成工业株式会社 2020-05-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11472823-B2 Tetrazole silane compound, method for synthesizing said compound and use thereof TST, ITGA5, TPX2 ALDH1A1 1587/4885MEN1 2187/4885KMT2A 735/4885
US-10975108-B2 ITGA5, ITGB5, ITGA1 ALDH1A1 845/4885MEN1 2534/4885KMT2A 983/4885
US-20200223875-A1 TETRAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF TST, ITGA5, TPX2 ALDH1A1 1587/4885MEN1 2187/4885KMT2A 735/4885
US-11014946-B2 Tetrazole silane compound, method for synthesizing said compound and use thereof TST, ITGA5, TPX2 ALDH1A1 1587/4885MEN1 2187/4885KMT2A 735/4885
US-20210179642-A1 TETRAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF TST, ITGA5, TPX2 ALDH1A1 1587/4885MEN1 2187/4885KMT2A 735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.