SCHEMBL222067

SCHEMBL222067

CC1=CCC2C3C=CC(C3)C12

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
MAPK1 P28482 1/20 0.36
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 1/20 0.33
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9063836 0.74 ALDH1A1 (0.38) TSHRMAPK1ALDH1A1TDP1
SCHEMBL4102173 0.74 ALDH1A1 (0.35) ALDH1A1TDP1
SCHEMBL4099322 0.74 ALDH1A1 (0.35) TSHRALDH1A1TDP1CYP3A4
SCHEMBL4107952 0.74 ALDH1A1 (0.32) ALDH1A1TDP1KDM4E
SCHEMBL19275058 0.72 ALDH1A1 (0.34) ALDH1A1TDP1
SCHEMBL5836251 0.70 ALDH1A1 (0.35) ALDH1A1
SCHEMBL4104189 0.68 HSD11B1 (0.34) ALDH1A1
SCHEMBL4099177 0.67 SMN1; SMN2 (0.42) TSHRALDH1A1TDP1CYP3A4CYP2C19
SCHEMBL9278739 0.67 KMT2A (0.35) MAPK1ALDH1A1TDP1CYP3A4CYP2C19
SCHEMBL4105713 0.67 ALDH1A1 (0.36) TSHRMAPK1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 812 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120219776-A1 Multilayer Films Containing Polyolefin-Interpolymer Resin Particle Blends NOVA CHEMICALS INC. (US) 2012-08-30 US claimed
WO-2025201399-A1 Sustainable AABB Polyamide for flame-retardant applications BASF SE (DE) 2025-10-02 WO disclosed
EP-4577599-A1 FLAME-RETARDANT POLYAMIDE COMPOSITION BASF SE (DE) 2025-07-02 EP disclosed
US-20250206912-A1 COMPOSITIONS COMPRISING POLY(ARYLENE ETHER SULFONES) BASF SE (DE) 2025-06-26 US disclosed
CN-119768460-A Flame retardant polyamide composition 巴斯夫欧洲公司 2025-04-04 CN disclosed
US-20250019542-A1 COMPOSITIONS COMPRISING POLYARYLENE(ETHER)SULFONES BASF SE (DE) 2025-01-16 US disclosed
CN-115210319-B Heat-resistant polyamide moulding compositions 巴斯夫欧洲公司 2024-12-06 CN disclosed
CN-118974979-A Compositions comprising poly (arylene ether sulfone) 巴斯夫欧洲公司 2024-11-15 CN disclosed
CN-115335456-B Heat-aging-resistant polyamide molding compositions 巴斯夫欧洲公司 2024-10-29 CN disclosed
US-12129938-B2 Tube and method for making same SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2024-10-29 US disclosed
EP-0193060-A2 Thermoplastic moulding compositions containing polysiloxane-polycarbonate block copolymers BAYER AG (DE) 1986-09-03 EP disclosed
US-4569970-A ABSTERPOLYMERS, POLYESTERS, ELASTOMERS MIXED BAYER AKTIENGESELLSCHAFT (DE) 1986-02-11 US disclosed
US-4515918-A LOW HEAT DISTORTION BAYER AKTIENGESELLSCHAFT (DE) 1985-05-07 US disclosed
EP-0135794-A2 Thermoplastic moulding materials of polysiloxane polycarbonate block copolymers BAYER AG (DE) 1985-04-03 EP disclosed
EP-0064689-A2 Thermoplastic moulding compositions on the basis of polycarbonate, poly(alkyleneterephthalate) and, possibly, one or more polymerizates BAYER AG (DE) 1982-11-17 EP disclosed
EP-0003812-B1 THERMO-ELASTIC BLEND OF POLYOLEFINES WITH PARTIALLY CROSS-LINKED ETHYLENE-PROPYLENE COPOLYMERS BAYER AG (DE) 1982-03-24 EP disclosed
US-4210579-A Thermoplastic mixtures of polypropylene with ethylene/vinyl acetate and ethylene/propylene copolymers BAYER AKTIENGESELLSCHAFT (DE) 1980-07-01 US disclosed
EP-0004313-A2 Thermoplastic blends of polypropylene and copolymers of both ethylene-vinylacetate and ethylene-propylene BAYER AG (DE) 1979-10-03 EP disclosed
EP-0003812-A2 Thermo-elastic blend of polyolefines with partially cross-linked ethylene-propylene copolymers BAYER AG (DE) 1979-09-05 EP disclosed
US-4154720-A SULFUR VULCANIZATION, ZINC OXIDE ACTIVATOR STANDARD OIL COMPANY (INDIANA) (US) 1979-05-15 US disclosed