Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CASP1 | P29466 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 1/20 | 1.00 |
| ▸ | ESR1 | P03372 | 1/20 | 1.00 |
| ▸ | PGR | P06401 | 1/20 | 1.00 |
| ▸ | ADRB2 | P07550 | 1/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 1/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 1/20 | 1.00 |
| ▸ | HTR1A | P08908 | 1/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 1/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 1.00 |
| ▸ | NQO2 | P16083 | 1/20 | 1.00 |
| ▸ | MAOA | P21397 | 1/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 1/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 1/20 | 1.00 |
| ▸ | MAOB | P27338 | 1/20 | 1.00 |
| ▸ | PDE4A | P27815 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Primaquine SCHEMBL22208 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1CYP1A2CASP1TP53 | |
| Primaquine SCHEMBL12599100 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1CYP1A2CASP1TP53 | |
| Primaquine SCHEMBL29409423 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1CYP1A2CASP1TP53 | |
| Primaquine SCHEMBL979493 | 0.99 | KDM4E (0.98) | KDM4EALDH1A1CYP1A2CASP1TP53 | |
| Primaquine SCHEMBL6333949 | 0.99 | KDM4E (0.98) | KDM4EALDH1A1CYP1A2CASP1TP53 | |
| Primaquine SCHEMBL4959404 | 0.99 | KDM4E (0.98) | KDM4EALDH1A1CYP1A2CASP1TP53 | |
| Primaquine SCHEMBL9240759 | 0.96 | KDM4E (0.92) | KDM4EALDH1A1CYP1A2CASP1TP53 | |
| Primaquine SCHEMBL4954948 | 0.95 | KDM4E (0.90) | KDM4EALDH1A1CYP1A2CASP1TP53 | |
| Primaquine SCHEMBL41097 | 0.94 | KDM4E (1.00) | KDM4EALDH1A1CYP1A2CASP1TP53 | |
| Primaquine SCHEMBL29576219 | 0.94 | KDM4E (1.00) | KDM4EALDH1A1CYP1A2CASP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 11561 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3607938-B1 | PHARMACEUTICAL COMPOSITION | SOVIC BRKICIC LJILJANA (HR) | 2026-05-27 | — | — | EP | claimed |
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| EP-4727549-A2 | PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS | University of Georgia Research Foundation, Inc. (US) | 2026-04-22 | — | — | EP | claimed |
| US-12582694-B2 | Compounds and methods for inhibiting protozoan parasites | UNIVERSITY OF SOUTH FLORIDA (US) | 2026-03-24 | — | — | US | claimed |
| EP-4680608-A1 | 2,6-DIHYDRO-7H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE DERIVATIVES AS ANTI-MALARIAL AGENTS | MMV Medicines for Malaria Venture (CH) | 2026-01-21 | — | — | EP | claimed |
| US-12509439-B2 | Anti-malarial agents | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2025-12-30 | — | — | US | claimed |
| US-20250388603-A1 | ANTIMALARIAL COMPOUNDS | SCRIPPS RESEARCH INST (US) | 2025-12-25 | — | — | US | claimed |
| EP-4659817-A2 | LIPOSOME COMPOSITION FOR USE IN PERITONEAL DIALYSIS | Versantis AG (CH) | 2025-12-10 | — | — | EP | claimed |
| WO-2025244856-A1 | METHODS AND COMPOSITIONS RELATING TO ELQ COMPOUNDS | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2025-11-27 | — | — | WO | claimed |
| EP-3625238-B1 | NOVEL SPIRO-LACTAM COMPOUNDS, PROCESS AND USES THEREOF | UNIV DE COIMBRA (PT) | 2025-11-26 | — | — | EP | claimed |
| US-4416872-A | INTERRUPTING LIFE CYCLE OF THE PARASITE IN LIVER OF HOST | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1983-11-22 | — | — | US | claimed |
| US-4394444-A | PYRIDINE NUCLEOTIDE, PEROXIDASE | MILES LABORATORIES, INC. (US) | 1983-07-19 | — | — | US | claimed |
| US-4376765-A | Medicaments, their preparation and compositions containing same | INSTITUT INTERNATIONAL DE PATHOLOGIE CELLULAIRE ET MOLECULAIRE (BE) | 1983-03-15 | — | — | US | claimed |
| US-4302459-A | Liposome carriers in leishmaniasis chemotherapy with 8-aminoquinoline derivatives | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1981-11-24 | — | — | US | claimed |
| EP-0037175-A1 | Pharmaceutical compositions | EFAMOL LIMITED (GB) | 1981-10-07 | — | — | EP | claimed |
| EP-0037388-A2 | Pharmaceutical forms, their preparation and compositions containing the same | INSTITUT INTERNATIONAL DE PATHOLOGIE CELLULAIRE ET MOLECULAIRE (BE) | 1981-10-07 | — | — | EP | claimed |
| EP-0035856-A2 | Pharmaceutical and dietary compositions | EFAMOL LIMITED (GB) | 1981-09-16 | — | — | EP | claimed |
| EP-0001796-B1 | ANTI-MALARIA DRUG | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-10 | — | — | EP | claimed |
| EP-0001796-A1 | Anti-malaria drug | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-16 | — | — | EP | claimed |
| US-4074972-A | Urea assay | AMERICAN MONITOR CORPORATION (US) | 1978-02-21 | — | — | US | claimed |