SCHEMBL222072

SCHEMBL222072

C=CC(=O)OCC(C)(C)CN(C)C

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
TP53 P04637 3/20 0.48
HIF1A Q16665 3/20 0.48
CYP3A4 P08684 2/20 0.48
MAPK1 P28482 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TSHR P16473 7/20 0.41
THRB P10828 2/20 0.41
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18071331 0.84 ALDH1A1 (0.44) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL262028 0.84 ALDH1A1 (0.59) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL373277 0.82 ALDH1A1 (0.46) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL11096298 0.81 ALDH1A1 (0.44) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL13768861 0.79
SCHEMBL1353827 0.79 ALDH1A1 (0.53) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL9576144 0.79 ALDH1A1 (0.53) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL7107705 0.79 ALDH1A1 (0.64) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL230726 0.79 ALDH1A1 (0.64) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL4632473 0.79 ALDH1A1 (0.53) ALDH1A1TP53HIF1ACYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 386 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210284542-A1 RECYCLABLE AND/OR REUSABLE POLYMER TEMPLATES FOR PRODUCING HOLLOW SILICA PARTICLES UNIV KING ABDULLAH SCI & TECH (SA) 2021-09-16 US claimed
EP-3818011-A1 RECYCLABLE AND/OR REUSABLE POLYMER TEMPLATES FOR PRODUCING HOLLOW SILICA PARTICLES King Abdullah University of Science and Technology (SA) 2021-05-12 EP claimed
WO-2020008371-A1 RECYCLABLE AND/OR REUSABLE POLYMER TEMPLATES FOR PRODUCING HOLLOW SILICA PARTICLES KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2020-01-09 WO claimed
US-9724288-B2 Copolymers useful as rheology modifiers and home and personal care compositions comprising said copolymers BASF SE (DE) 2017-08-08 US claimed
US-20160338939-A1 COPOLYMERS USEFUL AS RHEOLOGY MODIFIERS AND HOME AND PERSONAL CARE COMPOSITIONS COMPRISING SAID COPOLYMERS BASF SE (DE) 2016-11-24 US claimed
EP-1958610-B1 Method of permanently deforming keratinous fibres including an application step involving an oxidising composition containing a cationic thickening polymer ORÉAL L (FR) 2016-08-10 EP claimed
US-8916058-B2 Fluorobetaine copolymer and fire fighting foam concentrates therefrom E I DU PONT DE NEMOURS AND COMPANY (US) 2014-12-23 US claimed
EP-1987083-B1 POLYMERIZABLE SILICONE COPOLYOL MACROMERS AND POLYMERS MADE THEREFROM LUBRIZOL ADVANCED MAT INC (US) 2014-08-27 EP claimed
EP-2328547-B1 COPOLYMERS USEFUL AS RHEOLOGY MODIFIERS AND HOME AND PERSONAL CARE COMPOSITIONS BASF SE (DE) 2014-03-05 EP claimed
US-20130137844-A1 Polymerizable Silicone Copolyol Macromers And Polymers Made Therefrom LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-05-30 US claimed
WO-2004024779-A2 MULTI-PURPOSE CATIONIC AND ASSOCIATIVE POLYMERS AND COMPOSITIONS CONTAINING THEM AND THEIR METHOD OF PREPARATION NOVEON IP HOLDINGS CORP. (US) 2004-03-25 WO claimed
US-20040052746-A1 Multi-purpose polymers, methods and compositions LUBRIZOL ADVANCED MATERIALS, INC. 2004-03-18 US claimed
JP-2003529640-A 2003-10-07 JP claimed
US-6576255-B1 Injection molding method for (meth)acrylate copolymers having tertiary ammonium groups ROEHM GMBH & CO. KG (DE) 2003-06-10 US claimed
EP-0710680-B1 Aqueous polymer dispersion BASF AG (DE) 2003-03-19 EP claimed
EP-1268214-A1 INK RECEPTIVE COATING COMPOSITIONS CONTAINING POLY(VINYL ALCOHOL) GRAFTED WITH AMINE FUNCTIONAL GROUPS Celanese International Corporation (US) 2003-01-02 EP claimed
US-6455134-B1 2-(DIMETHYLAMINO)ETHYL METHACRYLATE-VINYL ACETATE TYPE COPOLYMERS; POLYVINYL ALCOHOL COLLOID STABILIZER; HIGH OPTICAL DENSITY IMAGES AIR PRODUCTS POLYMERS, L.P. 2002-09-24 US claimed
US-6348256-B1 HIGH OPTICAL DENSITY IMAGES; WATER RESISTANCE CELANESE INTERNATIONAL CORPORATION 2002-02-19 US claimed
WO-2001074599-A1 INK RECEPTIVE COATING COMPOSITIONS CONTAINING POLY(VINYL ALCOHOL) GRAFTED WITH AMINE FUNCTIONAL GROUPS CELANESE INTERNATIONAL CORPORATION (US) 2001-10-11 WO claimed
EP-0126866-A1 Organic amine salt of an acid, manufacture and use as accelerator DENTSPLY INTERNATIONAL, INC. (US) 1984-12-05 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160338939-A1 COPOLYMERS USEFUL AS RHEOLOGY MODIFIERS AND HOME AND PERSONAL CARE COMPOSITIONS COMPRISING SAID COPOLYMERS PHLPP1, PHLPP2, F12 ALDH1A1 4570/4885TP53 1614/4885HIF1A 2344/4885
US-20040052746-A1 Multi-purpose polymers, methods and compositions PLOD3, PARN, PARG ALDH1A1 4070/4885TP53 1259/4885HIF1A 3426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.