Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096298 | 0.85 | ALDH1A1 (0.44) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL222072 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL262028 | 0.81 | ALDH1A1 (0.59) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL1353827 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL31232973 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL18071331 | 0.78 | ALDH1A1 (0.44) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL18495622 | 0.77 | TSHR (0.50) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| Propanol SCHEMBL7030793 | 0.77 | ALDH1A1 (0.55) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL1245587 | 0.76 | THRB (0.41) | ALDH1A1THRBTSHRPAX8 | |
| SCHEMBL230726 | 0.76 | ALDH1A1 (0.64) | ALDH1A1TP53HIF1ACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576255-B1 | Injection molding method for (meth)acrylate copolymers having tertiary ammonium groups | ROEHM GMBH & CO. KG (DE) | 2003-06-10 | — | — | US | claimed |
| US-20220287345-A1 | SOLUBILITY ENHANCEMENT OF POORLY SOLUBLE ACTIVES | EVONIK OPERATIONS GMBH (DE) | 2022-09-15 | — | — | US | disclosed |
| EP-4009961-A1 | SOLUBILITY ENHANCEMENT OF POORLY SOLUBLE ACTIVES | Evonik Operations GmbH (DE) | 2022-06-15 | — | — | EP | disclosed |
| WO-2021023857-A1 | SOLUBILITY ENHANCEMENT OF POORLY SOLUBLE ACTIVES | EVONIK OPERATIONS GMBH (DE) | 2021-02-11 | — | — | WO | disclosed |
| US-20190224130-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING HYDROMORPHONE AND NALOXONE | PURDUE PHARMA (CA) | 2019-07-25 | — | — | US | disclosed |
| EP-3505162-A1 | USE OF BINDERS FOR MANUFACTURING STORAGE STABLE FORMULATIONS | Euro-Celtique S.A. (LU) | 2019-07-03 | — | — | EP | disclosed |
| US-10113050-B2 | Powdery or granulated composition comprising a copolymer, a dicarboxylic acid and a fatty monocarboxylic acid | EVONIK ROEHM GMBH (DE) | 2018-10-30 | — | — | US | disclosed |
| EP-2568967-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING HYDROMORPHONE AND NALOXONE | EURO CELTIQUE SA (LU) | 2018-10-24 | — | — | EP | disclosed |
| EP-2603205-B1 | USE OF BINDERS FOR MANUFACTURING STORAGE STABLE FORMULATIONS | EURO CELTIQUE SA (LU) | 2018-10-03 | — | — | EP | disclosed |
| EP-2568964-B1 | PHARMACEUTICAL DOSAGE FORM COMPRISING ONE OR MORE ANTIRETROVIRAL ACTIVE INGREDIENTS | EVONIK ROEHM GMBH (DE) | 2018-08-01 | — | — | EP | disclosed |
| US-20050281871-A1 | Methods for coating substrates for pharmaceutical uses with a mixture of two film-forming coating agents | ROEHM GMBH & CO. KG (DE) | 2005-12-22 | — | — | US | disclosed |
| US-20050271778-A1 | Method for producing coated pharmaceuticals and food supplements with concentration gradients in the coating thereof | ROEHM GMBH & CO., KG (DE) | 2005-12-08 | — | — | US | disclosed |
| US-20050142174-A1 | Adhesive and binding agent for dermal or transdermal treatment systems | ROEHM GMBH & CO. KG | 2005-06-30 | — | — | US | disclosed |
| US-20050019381-A1 | Binding agent which is stable in storage and used for pharmaceutical applications | ROEHM GMBH & CO. KG (DE) | 2005-01-27 | — | — | US | disclosed |
| US-6846891-B2 | Coating and binding agent for oral or dermal pharmaceutical forms | ROEHM GMBH & CO. KG (DE) | 2005-01-25 | — | — | US | disclosed |
| US-20040247687-A1 | Method for production of active ingredient-containing pellets | ROEHM GMBH & CO. KG (DE) | 2004-12-09 | — | — | US | disclosed |
| US-20030220413-A1 | Coating and binding agent for oral or dermal pharmaceutical forms | ROEHM GMBH & CO. KG (DE) | 2003-11-27 | — | — | US | disclosed |
| US-6624210-B1 | (Meth)acrylate ester copolymer with (meth)acrylate containing tertiary amine group, plasticizer, and emulsifier; powders, pastes, aqueous suspension; encapsulation; drug delivery | ROEHM GMBH & CO. KG (DE) | 2003-09-23 | — | — | US | disclosed |
| US-6576255-B1 | Injection molding method for (meth)acrylate copolymers having tertiary ammonium groups | ROEHM GMBH & CO. KG (DE) | 2003-06-10 | — | — | US | disclosed |
| US-4705695-A | AMMONIUM SALT OF TERTIARY AMINE SUBSTITUTED ACRYLIC POLYMER | ROHM GMBH CHEMISCHE FABRIK (DE) | 1987-11-10 | — | — | US | disclosed |