SCHEMBL2220772

SCHEMBL2220772

COc1cc2cc3ccccc3cc2c(S(=O)(=O)O)c1OC.c1ccc(-c2nccn2-c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK9 P45984 1/20 0.39
MAPK10 P53779 1/20 0.39
KDR P35968 6/20 0.39
TUBB4A P04350 2/20 0.39
TUBB P07437 2/20 0.39
TUBA3C P0DPH7 2/20 0.39
TUBA1B P68363 2/20 0.39
TUBA4A P68366 2/20 0.39
TUBB4B P68371 2/20 0.39
TUBB3 Q13509 2/20 0.39
TUBB2A Q13885 2/20 0.39
TUBB8 Q3ZCM7 2/20 0.39
TUBA3E Q6PEY2 2/20 0.39
TUBA1A Q71U36 2/20 0.39
TUBA1C Q9BQE3 2/20 0.39
TUBB6 Q9BUF5 2/20 0.39
TUBB2B Q9BVA1 2/20 0.39
TUBB1 Q9H4B7 2/20 0.39
FLT1 P17948 2/20 0.39
FLT4 P35916 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL5178781 0.82 HPGD (0.41) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL4238902 0.81 NQO1 (0.46) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL5178783 0.78 ALDH1A1 (0.40) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL2220777 0.74 PDGFRB (0.47) KDRFLT4KDM4EALDH1A1HPGD
SCHEMBL5950594 0.71 NQO1 (0.46) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL23382222 0.69 KDR (0.59) MAPK9MAPK10KDRFLT1FLT4
SCHEMBL30878105 0.69 KDR (0.59) MAPK9MAPK10KDRFLT1FLT4
SCHEMBL28186197 0.69 KDR (0.55) MAPK9MAPK10KDRFLT1FLT4
SCHEMBL11385870 0.69 KDR (0.58) MAPK9MAPK10KDRFLT1FLT4
SCHEMBL12077033 0.68 KDR (0.55) MAPK9MAPK10KDRFLT1FLT4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722758-B2 Water soluble polyimide resin, its preparation and use CHANG CHUN PLASTICS CO., LTD. (TW) 2014-05-13 US disclosed
US-20110172324-A1 NOVEL WATER SOLUBLE POLYIMIDE RESIN, ITS PREPARATION AND USE CHANG CHUN PLASTICS CO., LTD. (TW) 2011-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110172324-A1 NOVEL WATER SOLUBLE POLYIMIDE RESIN, ITS PREPARATION AND USE ARID2, PUF60, PADI4 MAPK9 805/4885MAPK10 2286/4885KDR 261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.