SCHEMBL22207757

SCHEMBL22207757

O=C(O)CNC(=O)COC1C#CCCCCC1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BBOX1 O75936 1/20 0.33
ASPH Q12797 1/20 0.33
KDM8 Q8N371 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
HIF1AN Q9NWT6 1/20 0.33
ALDH1A1 P00352 2/20 0.31
ITGB1 P05556 1/20 0.31
ITGA5 P08648 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22207764 0.97 BBOX1 (0.32) BBOX1ASPHKDM8EGLN1HIF1AN
SCHEMBL25304648 0.97 BBOX1 (0.32) BBOX1ASPHKDM8EGLN1HIF1AN
SCHEMBL22207761 0.97 BBOX1 (0.32) BBOX1ASPHKDM8EGLN1HIF1AN
SCHEMBL21978410 0.85 CYP2D6 (0.31)
SCHEMBL30943656 0.85
SCHEMBL13228012 0.84 EPHX1 (0.40) ALDH1A1
SCHEMBL17143691 0.84 NPSR1 (0.30)
SCHEMBL19201307 0.84 PTGDR2 (0.33)
SCHEMBL30153489 0.84 PTGDR2 (0.33)
SCHEMBL2618031 0.84 PTGDR2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113905767-A Traceless linkers and protein conjugates thereof 里珍纳龙药品有限公司 2022-01-07 CN disclosed
EP-3908323-A2 TRACELESS LINKERS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2021-11-17 EP disclosed
WO-2020146541-A2 TRACELESS LINKERS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2020-07-16 WO disclosed