Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.30 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2618031 | 1.00 | PTGDR2 (0.33) | PTGDR2LMNAPTGDRPTGER2 | |
| SCHEMBL30153489 | 1.00 | PTGDR2 (0.33) | PTGDR2LMNAPTGDRPTGER2 | |
| SCHEMBL31650890 | 0.98 | PTGDR2 (0.30) | PTGDR2 | |
| SCHEMBL13464242 | 0.85 | HTT (0.32) | — | |
| SCHEMBL15078950 | 0.85 | NPSR1 (0.31) | — | |
| SCHEMBL18106103 | 0.85 | — | — | |
| SCHEMBL22207757 | 0.84 | BBOX1 (0.33) | — | |
| SCHEMBL13154130 | 0.83 | CES2 (0.32) | — | |
| SCHEMBL17525150 | 0.83 | LMNA (0.36) | PTGDR2LMNA | |
| SCHEMBL18958958 | 0.82 | EPHX2 (0.36) | PTGDR2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017132103-A2 | PHOSPHONATE LINKERS AND THEIR USE TO FACILITATE CELLULAR RETENTION OF COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2017-08-03 | — | — | WO | disclosed |