SCHEMBL2618031

SCHEMBL2618031

O=C(O)COC1C#CCCCCC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 6/20 0.33
LMNA P02545 1/20 0.31
PTGDR Q13258 3/20 0.30
PTGER2 P43116 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19201307 1.00 PTGDR2 (0.33) PTGDR2LMNAPTGDRPTGER2
SCHEMBL30153489 1.00 PTGDR2 (0.33) PTGDR2LMNAPTGDRPTGER2
SCHEMBL31650890 0.98 PTGDR2 (0.30) PTGDR2
SCHEMBL13464242 0.85 HTT (0.32)
SCHEMBL15078950 0.85 NPSR1 (0.31)
SCHEMBL18106103 0.85
SCHEMBL22207757 0.84 BBOX1 (0.33)
SCHEMBL13154130 0.83 CES2 (0.32)
SCHEMBL17525150 0.83 LMNA (0.36) PTGDR2LMNA
SCHEMBL18958958 0.82 EPHX2 (0.36) PTGDR2PTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9981997-B2 Chemical reagents for attaching affinity molecules on surfaces ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-05-29 US claimed
US-20160280723-A1 CHEMICAL REAGENTS FOR ATTACHING AFFINITY MOLECULES ON SURFACES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2016-09-29 US claimed
CN-104672484-A Cross-linked polysaccharide tissue engineering porous scaffold preparation method UNIV NANJING SCIENCE & TECH 2015-06-03 CN claimed
EP-3946460-B1 IMPROVED CONJUGATION LINKERS PROLYNX LLC (US) 2026-05-20 EP disclosed
EP-3125943-B1 PHOSPHATE BASED LINKERS FOR INTRACELLULAR DELIVERY OF DRUG CONJUGATES MERCK SHARP & DOHME LLC (US) 2026-04-22 EP disclosed
US-20260020859-A1 MATERIALS FOR CONFORMABLE FILLABLE MEDICAL BALLOONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-01-22 US disclosed
US-20260021223-A1 HYDROGEL FILLERS FOR CONFORMABLE FILLABLE MEDICAL BALLOONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-01-22 US disclosed
US-20260007768-A1 CONJUGATION LINKERS PROLYNX LLC (US) 2026-01-08 US disclosed
US-20250248935-A1 SYSTEMS AND METHODS FOR ON-DEMAND CLEAVAGE OF HYDROGELS BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-08-07 US disclosed
US-12364771-B2 Conjugation linkers PROLYNX LLC (US) 2025-07-22 US disclosed
US-12312574-B2 Polymer-coated crosslinked alginate gel fiber MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2025-05-27 US disclosed
US-7807619-B2 cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-10-05 US disclosed
US-7807619-B2 cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-10-05 US disclosed
WO-2010106246-A1 METHOD FOR SURFACE FUNCTIONALISATION BY DISUBSTITUTED ALKYNES COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2010-09-23 WO disclosed
WO-2010106245-A1 NOVEL BIFUNCTIONAL MOLECULES COMPRISING A CYCLOALKYNE OR HETEROCYCLOALKYNE GROUP AND A REDOX GROUP COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2010-09-23 WO disclosed
US-20100200813-A1 SEMICONDUCTOR NANOCRYSTALS COMMISSARIAT A L' ENERGIE ATOMIQUE (FR) 2010-08-12 US disclosed
US-20100200813-A1 SEMICONDUCTOR NANOCRYSTALS COMMISSARIAT A L' ENERGIE ATOMIQUE (FR) 2010-08-12 US disclosed
EP-2161239-A1 Semiconductor nanocrystals Commissariat à l'Energie Atomique (FR) 2010-03-10 EP disclosed
US-20090068738-A1 COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-03-12 US disclosed
US-20090068738-A1 COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250248935-A1 SYSTEMS AND METHODS FOR ON-DEMAND CLEAVAGE OF HYDROGELS PLG, FGB, ADAM33 PTGDR2 2305/4885LMNA 117/4885PTGDR 2297/4885
US-20260021223-A1 HYDROGEL FILLERS FOR CONFORMABLE FILLABLE MEDICAL BALLOONS H1-5, H1-2, H1-3 PTGDR2 1725/4885LMNA 1262/4885PTGDR 1972/4885
US-20260020859-A1 MATERIALS FOR CONFORMABLE FILLABLE MEDICAL BALLOONS SMCHD1, KDM8, H1-5 PTGDR2 1806/4885LMNA 1485/4885PTGDR 2003/4885
US-20090068738-A1 COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES PTMS, QPCT, ANPEP PTGDR2 1144/4885LMNA 1871/4885PTGDR 458/4885
US-20260007768-A1 CONJUGATION LINKERS OGFR, SLC43A1, ILK PTGDR2 1336/4885LMNA 3011/4885PTGDR 590/4885
US-20160280723-A1 CHEMICAL REAGENTS FOR ATTACHING AFFINITY MOLECULES ON SURFACES EPCAM, ICAM1, SELE PTGDR2 1836/4885LMNA 3359/4885PTGDR 1882/4885
US-12364771-B2 Conjugation linkers DNPEP, FGB, VIP PTGDR2 3785/4885LMNA 2524/4885PTGDR 3384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.