Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580101 | 1.00 | OPRM1 (0.44) | OPRM1OPRK1MEN1TSHRKMT2A | |
| SCHEMBL30064999 | 1.00 | OPRM1 (0.44) | OPRM1OPRK1MEN1TSHRKMT2A | |
| SCHEMBL22555109 | 1.00 | OPRM1 (0.44) | OPRM1OPRK1MEN1TSHRKMT2A | |
| SCHEMBL22555142 | 0.85 | PDK1 (0.47) | OPRM1OPRK1MEN1TSHRKMT2A | |
| SCHEMBL22555075 | 0.85 | PDK1 (0.47) | OPRM1OPRK1MEN1TSHRKMT2A | |
| SCHEMBL651151 | 0.82 | STS (0.47) | KMT2A | |
| SCHEMBL30071078 | 0.82 | STS (0.47) | KMT2A | |
| SCHEMBL929751 | 0.82 | STS (0.47) | KMT2A | |
| SCHEMBL29889592 | 0.79 | ABL1 (0.46) | OPRK1 | |
| SCHEMBL27816784 | 0.78 | BCHE (0.49) | MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4087573-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-11-16 | — | — | EP | disclosed |
| EP-3908283-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2021-11-17 | — | — | EP | disclosed |
| WO-2020146613-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2020-07-16 | — | — | WO | disclosed |