Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9596103 | 0.81 | ALDH1A1 (0.47) | ELANE | |
| SCHEMBL30071078 | 0.80 | STS (0.47) | — | |
| SCHEMBL651151 | 0.80 | STS (0.47) | — | |
| SCHEMBL929751 | 0.80 | STS (0.47) | — | |
| SCHEMBL7983086 | 0.79 | PDK1 (0.55) | S1PR5OPRD1OPRK1BCHEECE1 | |
| SCHEMBL7983089 | 0.79 | PDK1 (0.55) | S1PR5OPRD1OPRK1BCHEECE1 | |
| SCHEMBL7983083 | 0.79 | PDK1 (0.55) | S1PR5OPRD1OPRK1BCHEECE1 | |
| SCHEMBL22555109 | 0.79 | OPRM1 (0.44) | OPRK1 | |
| SCHEMBL22208222 | 0.79 | OPRM1 (0.44) | OPRK1 | |
| SCHEMBL30064999 | 0.79 | OPRM1 (0.44) | OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4322945-A2 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |
| WO-2022221528-A2 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-10-20 | — | — | WO | disclosed |