SCHEMBL2220867

SCHEMBL2220867

O=C(O)N(CCc1ccc(O)c(O)c1)C(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC1 P07992 3/20 0.49
ERCC4 Q92889 3/20 0.49
ALOX15 P16050 3/20 0.49
IGF1R P08069 2/20 0.49
GAA P10253 3/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
CCR5 P51681 1/20 0.47
LCK P06239 2/20 0.46
HIF1A Q16665 3/20 0.45
HSD17B10 Q99714 3/20 0.45
TSHR P16473 2/20 0.45
NFKB1 P19838 2/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
DRD2 P14416 1/20 0.45
DRD1 P21728 1/20 0.45
DRD4 P21917 1/20 0.45
DRD5 P21918 1/20 0.45
ADRA1D P25100 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2219811 0.79 IGF1R (0.60) ERCC1ERCC4ALOX15IGF1RLCK
SCHEMBL3289317 0.74 HIF1A (0.57) ALOX15IGF1RGAALCKHIF1A
SCHEMBL31520989 0.73 OPRK1 (0.61) ALOX15IGF1RGAAHIF1AHSD17B10
SCHEMBL11755956 0.73 OPRK1 (0.61) ALOX15IGF1RGAAHIF1AHSD17B10
SCHEMBL30323320 0.73 IGF1R (0.56) ERCC1ERCC4ALOX15IGF1RGAA
SCHEMBL7544044 0.71 IGF1R (0.57) ALOX15IGF1RMEN1KMT2AHIF1A
SCHEMBL30874767 0.71 ALOX15 (0.47) ALOX15IGF1RGAALCKHIF1A
SCHEMBL8804207 0.71 LCK (0.50) ERCC1ERCC4ALOX15IGF1RGAA
SCHEMBL14219226 0.70 MLYCD (0.49) MEN1KMT2AMAPTTDP1ALDH1A1
SCHEMBL14241207 0.70 HIF1A (0.60) ALOX15IGF1RGAALCKHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10266620-B2 Coating agents and coated articles INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) 2019-04-23 US disclosed
US-20170081435-A1 COATING AGENTS AND COATED ARTICLES INNOVATIVE SURFACE TECH INC (US) 2017-03-23 US disclosed
US-9539371-B2 Coating agents and coated articles INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) 2017-01-10 US disclosed
EP-2516567-B1 COATING AGENTS AND COATED ARTICLES INNOVATIVE SURFACE TECHNOLOGIES INC (US) 2016-08-03 EP disclosed
US-20150359944-A1 COATING AGENTS AND COATED ARTICLES INNOVATIVE SURFACE TECHNOLOGIES INC (US) 2015-12-17 US disclosed
EP-2516567-A1 COATING AGENTS AND COATED ARTICLES Innovative Surface Technologies, Inc. (US) 2012-10-31 EP disclosed
US-20120258313-A1 COATING AGENTS AND COATED ARTICLES INNOVATIVE SURFACE TECHNOLOGIES, INC. 2012-10-11 US disclosed
WO-2011084811-A1 COATING AGENTS AND COATED ARTICLES INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) 2011-07-14 WO disclosed