Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.55 |
| ▸ | TYR | P14679 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22208890 | 0.86 | ALDH1A1 (0.51) | BCHETYRACHEBLMGAA | |
| SCHEMBL6551806 | 0.81 | TSHR (0.67) | BCHETYRACHETSHRBLM | |
| SCHEMBL4441784 | 0.80 | ACHE (0.51) | BCHETYRACHETSHRBLM | |
| SCHEMBL6698808 | 0.77 | ACP3 (0.53) | NPSR1CYP3A4ALDH1A1TDP1MAPT | |
| SCHEMBL30491037 | 0.76 | BCHE (0.73) | BCHETYRACHETSHRBLM | |
| SCHEMBL1594982 | 0.76 | BCHE (0.64) | BCHETYRACHETSHRBLM | |
| SCHEMBL5072122 | 0.76 | BCHE (0.73) | BCHETYRACHETSHRBLM | |
| SCHEMBL30343469 | 0.76 | BCHE (0.64) | BCHETYRACHETSHRBLM | |
| SCHEMBL1595318 | 0.76 | BCHE (0.64) | BCHETYRACHETSHRBLM | |
| SCHEMBL30343445 | 0.76 | BCHE (0.64) | BCHETYRACHETSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3908278-A1 | LEUKOTRIENE SYNTHESIS INHIBITORS | Naegis Pharmaceuticals Inc. (CA) | 2021-11-17 | — | — | EP | disclosed |
| WO-2020146822-A1 | LEUKOTRIENE SYNTHESIS INHIBITORS | NAEGIS PHARMACEUTICALS INC. (CA) | 2020-07-16 | — | — | WO | disclosed |