Cyclohexane

Cyclohexane

SCHEMBL2220928

C1CCCCC1.Oc1ccccc1C(O)O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.52
GABRB2 P47870 1/20 0.52
TSHR P16473 2/20 0.46
HPGD P15428 5/20 0.43
ALDH1A1 P00352 5/20 0.43
HSD17B10 Q99714 4/20 0.43
ALOX15 P16050 4/20 0.43
MAPT P10636 4/20 0.43
POLB P06746 3/20 0.43
HIF1A Q16665 2/20 0.43
KDM4E B2RXH2 2/20 0.43
NPC1 O15118 2/20 0.43
CA2 P00918 2/20 0.43
LMNA P02545 2/20 0.43
CA4 P22748 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
CA12 O43570 1/20 0.43
GMNN O75496 1/20 0.43
EGFR P00533 1/20 0.43
FYN P06241 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196228 0.92 GABRA1 (0.59) GABRA1GABRB2TSHRHPGDALDH1A1
SCHEMBL2219917 0.84 GABRA1 (0.46) GABRA1GABRB2TSHRHPGDALDH1A1
SCHEMBL11504087 0.78 GABRA1 (0.62) GABRA1GABRB2TSHRHPGDALDH1A1
SCHEMBL30195663 0.78 GABRA1 (0.62) GABRA1GABRB2TSHRHPGDALDH1A1
Cyclohexane SCHEMBL28002549 0.78 GABRA1 (0.86) GABRA1GABRB2TSHRHPGDALDH1A1
SCHEMBL8036927 0.74 GABRA1 (0.42) GABRA1GABRB2TSHRHPGDALDH1A1
SCHEMBL28064364 0.74 GABRA1 (0.42) GABRA1GABRB2TSHRHPGDALDH1A1
SCHEMBL14803860 0.74 GABRA1 (0.41) GABRA1GABRB2TSHRHPGDALDH1A1
Catechol SCHEMBL29002792 0.74 ALDH1A1 (0.77) TSHRHPGDALDH1A1HSD17B10ALOX15
Catechol SCHEMBL10621943 0.74 ALDH1A1 (0.77) TSHRHPGDALDH1A1HSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9081353-B2 Cleaner, and process cartridge and image forming apparatus using the cleaner RICOH COMPANY, LTD. (JP) 2015-07-14 US disclosed
US-20140193172-A1 CLEANER, AND PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS USING THE CLEANER RICOH COMPANY, LTD. (JP) 2014-07-10 US disclosed
US-20110173807-A1 DISPERSION FOR DISPOSING FINE PARTICLE AT PREDETERMINED POINT ON SUBSTRATE BY INK-JET PRINTING NATOCO CO., LTD. (JP) 2011-07-21 US disclosed