Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.39 |
| ▸ | PPARD | Q03181 | 5/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 3/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PRKX | P51817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2223974 | 0.90 | S1PR1 (0.49) | S1PR1PTPN1PPARDPPARAPPARG | |
| SCHEMBL14797067 | 0.85 | S1PR1 (0.70) | S1PR1PTPN1PPARDPPARAPPARG | |
| SCHEMBL2225306 | 0.84 | S1PR1 (0.54) | S1PR1PTPN1PPARGALDH1A1 | |
| SCHEMBL2223451 | 0.82 | S1PR1 (0.45) | S1PR1CETPKMT2A | |
| SCHEMBL15966895 | 0.80 | S1PR1 (0.54) | S1PR1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL2224272 | 0.79 | S1PR1 (0.55) | S1PR1PTPN1CETPKDM4EMEN1 | |
| SCHEMBL2222684 | 0.79 | S1PR1 (0.48) | S1PR1MAPTKMT2A | |
| SCHEMBL2224142 | 0.78 | S1PR1 (0.51) | S1PR1CETPMEN1ALDH1A1MAPT | |
| SCHEMBL2227168 | 0.77 | S1PR1 (0.52) | S1PR1PTPN1CETPCLK4KDM4E | |
| SCHEMBL2222853 | 0.75 | S1PR1 (0.58) | S1PR1CETPMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523962-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086079-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |