Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.55 |
| ▸ | CETP | P11597 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 2/20 | 0.35 |
| ▸ | UTRN | P46939 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2223974 | 0.89 | S1PR1 (0.49) | S1PR1CETPALDH1A1KDM4ENPSR1 | |
| SCHEMBL2226291 | 0.88 | S1PR1 (0.55) | S1PR1CETPMAPTEGFRBTK | |
| SCHEMBL2228933 | 0.87 | S1PR1 (0.58) | S1PR1CETPALDH1A1LMNAKMT2A | |
| SCHEMBL2224650 | 0.86 | S1PR1 (0.58) | S1PR1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL14797208 | 0.86 | S1PR1 (0.77) | S1PR1CETPKDM4ENPSR1MAPT | |
| SCHEMBL2223355 | 0.85 | S1PR1 (0.73) | S1PR1ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL2224909 | 0.83 | S1PR1 (0.58) | S1PR1ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL2269044 | 0.83 | S1PR1 (0.55) | S1PR1ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL2223341 | 0.82 | S1PR1 (0.54) | S1PR1ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL2225909 | 0.82 | S1PR1 (0.54) | S1PR1ALDH1A1KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523962-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086079-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |