Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.45 |
| ▸ | CETP | P11597 | 6/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2222684 | 0.88 | S1PR1 (0.48) | S1PR1MRGPRX1POLBGAAKMT2A | |
| SCHEMBL14797002 | 0.85 | S1PR1 (0.65) | S1PR1CETPRORC | |
| SCHEMBL2221033 | 0.82 | S1PR1 (0.49) | S1PR1CETPKMT2A | |
| SCHEMBL2229154 | 0.78 | ESR1 (0.47) | S1PR1CETPMRGPRX1ESR1ESR2 | |
| SCHEMBL14797111 | 0.78 | S1PR1 (0.65) | S1PR1CETP | |
| SCHEMBL2225375 | 0.78 | S1PR1 (0.44) | S1PR1ESR1ESR2POLBGAA | |
| SCHEMBL14797332 | 0.77 | S1PR1 (0.69) | S1PR1CETP | |
| SCHEMBL2222186 | 0.77 | S1PR1 (0.48) | S1PR1 | |
| SCHEMBL2224919 | 0.77 | S1PR1 (0.49) | S1PR1CETPGAA | |
| SCHEMBL2225306 | 0.76 | S1PR1 (0.54) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523962-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086079-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |