Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7581332 | 0.79 | SIRT6 (0.46) | NNMTSIRT6DGAT1SOAT1ADORA3 | |
| SCHEMBL30441778 | 0.79 | SIRT6 (0.46) | NNMTSIRT6DGAT1SOAT1ADORA3 | |
| SCHEMBL30644648 | 0.71 | SIRT6 (0.40) | NNMTSIRT6DGAT1SOAT1ADORA3 | |
| SCHEMBL31156762 | 0.71 | SIRT6 (0.40) | SIRT6DGAT1SOAT1ADORA3TSHR | |
| SCHEMBL31696048 | 0.71 | SIRT6 (0.40) | SIRT6DGAT1SOAT1ADORA3TSHR | |
| SCHEMBL15542179 | 0.70 | SIRT6 (0.42) | NNMTSIRT6DGAT1SOAT1ADORA3 | |
| SCHEMBL17084504 | 0.70 | JAK3 (0.35) | JAK2 | |
| SCHEMBL14525218 | 0.69 | KIT (0.40) | NNMTKITFLT3DGAT1ACHE | |
| SCHEMBL31046828 | 0.69 | DGAT1 (0.49) | SIRT6DGAT1SOAT1CNR1 | |
| SCHEMBL30802800 | 0.68 | NNMT (0.55) | NNMTSIRT6KITFLT3ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011083315-A1 | COMPOUNDS AND THEIR USE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-07-14 | — | — | WO | disclosed |