Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848297 | 0.86 | TSHR (0.61) | TSHRLMNAKDM4ECA12CA14 | |
| SCHEMBL1518251 | 0.86 | TSHR (0.68) | TSHRLMNAKDM4ECA12CA14 | |
| SCHEMBL25187 | 0.84 | TSHR (0.81) | TSHRLMNAKDM4ECA12CA14 | |
| SCHEMBL10481290 | 0.84 | TSHR (0.81) | TSHRLMNAKDM4ECA12CA14 | |
| SCHEMBL10021631 | 0.83 | TSHR (0.62) | TSHRLMNAKDM4ECA12CA14 | |
| SCHEMBL10481289 | 0.81 | TSHR (0.77) | TSHRLMNAKDM4ECA12CA14 | |
| Dimethyl Succinate SCHEMBL10213 | 0.81 | TSHR (1.00) | TSHRLMNAKDM4ECA12CA14 | |
| Dimethyl Succinate SCHEMBL28054469 | 0.81 | TSHR (1.00) | TSHRLMNAKDM4ECA12CA14 | |
| SCHEMBL11219823 | 0.79 | ALDH1A1 (0.43) | TSHRLMNAKDM4EALDH1A1 | |
| SCHEMBL6560703 | 0.79 | TSHR (0.72) | TSHRLMNAKDM4ECA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107857740-A | The synthetic method of the thiazolyl acetic acid of 2 sulfydryl of Cefodizime Sodium intermediate, 4 methyl 5 | 山东金城医药化工有限公司 | 2018-03-30 | — | — | CN | claimed |
| US-7339073-B2 | Method for obtaining 5-halogenolaevulinic acid alkyl esters | ALDENKORTT SVEN | 2008-03-04 | — | — | US | claimed |
| US-7319164-B2 | 5-azido-laevulinic acid, method for the production thereof and its use | ALDENKORTT SVEN | 2008-01-15 | — | — | US | claimed |
| EP-1353900-B1 | 5-AZIDO-LAEVULINIC ACID, METHOD FOR THE PRODUCTION THEREOF AND ITS USE | ALDENKORTT SVEN (DE) | 2006-10-04 | — | — | EP | claimed |
| US-20060086443-A1 | 5-azido-laevulinic acid, method for the production thereof and its use | ALDENKORTT SVEN | 2006-04-27 | — | — | US | claimed |
| US-20050070727-A1 | Method for obtaining 5-halogenolaevulinic acid alkyl esters | ALDENKORTT DR SVEN (DE) | 2005-03-31 | — | — | US | claimed |
| EP-3705480-B1 | CLASS OF AMINO-SUBSTITUTED NITROGEN-CONTAINING FUSED RING COMPOUNDS, PREPARATION METHOD THEREFOR, AND USE THEREOF | SHANGHAI RINGENE BIOPHARMA CO LTD (CN) | 2024-02-28 | — | — | EP | disclosed |
| CN-109721600-B | Nitrogen-containing fused ring compounds and preparation method and application thereof | 上海凌达生物医药有限公司 | 2021-04-27 | — | — | CN | disclosed |
| CN-109721599-B | Amino-substituted nitrogen-containing fused ring compound and preparation method and application thereof | 上海凌达生物医药有限公司 | 2020-12-15 | — | — | CN | disclosed |
| US-20200347061-A1 | CLASS OF AMINO-SUBSTITUTED NITROGEN-CONTAINING FUSED RING COMPOUNDS, PREPARATION METHOD THEREFOR, AND USE THEREOF | SHANGHAI RINGENE BIOPHARMA CO., LTD. (CN) | 2020-11-05 | — | — | US | disclosed |
| EP-3705480-A1 | CLASS OF AMINO-SUBSTITUTED NITROGEN-CONTAINING FUSED RING COMPOUNDS, PREPARATION METHOD THEREFOR, AND USE THEREOF | Rudong Ringene Pharmaceuticals, Co. Ltd (CN) | 2020-09-09 | — | — | EP | disclosed |
| CN-107857740-A | The synthetic method of the thiazolyl acetic acid of 2 sulfydryl of Cefodizime Sodium intermediate, 4 methyl 5 | 山东金城医药化工有限公司 | 2018-03-30 | — | — | CN | disclosed |
| CN-107857740-A | The synthetic method of the thiazolyl acetic acid of 2 sulfydryl of Cefodizime Sodium intermediate, 4 methyl 5 | 山东金城医药化工有限公司 | 2018-03-30 | — | — | CN | disclosed |
| EP-1461304-A2 | METHOD FOR OBTAINING 5-HALOGENOLAEVULINIC ACID ALKYL ESTERS | Mariotti, Antonia (DE) | 2004-09-29 | — | — | EP | disclosed |
| EP-1353900-A2 | 5-AZIDO-LAEVULINIC ACID, METHOD FOR THE PRODUCTION THEREOF AND ITS USE | Aldenkortt, Sven (DE) | 2003-10-22 | — | — | EP | disclosed |
| WO-2003045895-A3 | METHOD FOR OBTAINING 5-HALOGENOLAEVULINIC ACID ALKYL ESTERS | MARIOTTI ANTONIA (DE) | 2003-09-18 | — | — | WO | disclosed |
| WO-2003045895-A2 | METHOD FOR OBTAINING 5-HALOGENOLAEVULINIC ACID ALKYL ESTERS | MARIOTTI ANTONIA (DE) | 2003-06-05 | — | — | WO | disclosed |
| WO-2002053532-A3 | 5-AZIDO-LAEVULINIC ACID, METHOD FOR THE PRODUCTION THEREOF AND ITS USE | ALDENKORTT SVEN (DE) | 2003-03-13 | — | — | WO | disclosed |
| WO-2002053532-A2 | 5-AZIDO-LAEVULINIC ACID, METHOD FOR THE PRODUCTION THEREOF AND ITS USE | ALDENKORTT SVEN (DE) | 2002-07-11 | — | — | WO | disclosed |
| US-4000275-A | BENZIMIDAZO(2,1-B) QUINAZOLIN-12(6H)ONES | ELI LILLY AND COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200347061-A1 | CLASS OF AMINO-SUBSTITUTED NITROGEN-CONTAINING FUSED RING COMPOUNDS, PREPARATION METHOD THEREFOR, AND USE THEREOF | FGFR4, FGFR3, FGFR1 | TSHR 4079/4885LMNA 4179/4885KDM4E 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.