Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11756126 | 0.94 | TSHR (0.61) | TSHRLMNAKDM4EMGAMGAA | |
| SCHEMBL10481289 | 0.92 | TSHR (0.77) | TSHRLMNAKDM4EMGAMGAA | |
| SCHEMBL25187 | 0.88 | TSHR (0.81) | TSHRLMNAKDM4EMGAMGAA | |
| SCHEMBL10481290 | 0.88 | TSHR (0.81) | TSHRLMNAKDM4EMGAMGAA | |
| Dimethyl Succinate SCHEMBL9392460 | 0.85 | TSHR (0.87) | TSHRLMNAKDM4EMGAMGAA | |
| Dimethyl Succinate SCHEMBL10213 | 0.85 | TSHR (1.00) | TSHRLMNAKDM4EMGAMGAA | |
| Dimethyl Succinate SCHEMBL28054469 | 0.85 | TSHR (1.00) | TSHRLMNAKDM4EMGAMGAA | |
| SCHEMBL3768382 | 0.84 | PHF8 (0.58) | TSHRLMNAKDM4EMGAMGAA | |
| SCHEMBL2855916 | 0.84 | MGAM (0.67) | TSHRLMNAKDM4EMGAMGAA | |
| SCHEMBL11173057 | 0.84 | TSHR (0.75) | TSHRLMNAKDM4EMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078078-A1 | CONVERSION OF MUCONOLACTONE TO BETA-KETOADIPATES AND METHODS THEREFOR | U.S. DEPARTMENT OF ENERGY | 2026-03-19 | — | — | US | disclosed |
| CN-107074761-B | Process for producing epsilon-caprolactam | 东丽株式会社 | 2020-04-14 | — | — | CN | disclosed |
| US-20170107207-A1 | AMINOPYRAZOLONE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
| US-20170107207-A1 | AMINOPYRAZOLONE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
| US-20170107207-A1 | AMINOPYRAZOLONE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
| EP-3109239-A1 | AMINOPYRAZOLONE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-12-28 | — | — | EP | disclosed |
| CN-105980363-A | Aminopyrazolone Derivatives | 第三共株式会社 | 2016-09-28 | — | — | CN | disclosed |
| WO-2015125786-A1 | AMINOPYRAZOLONE DERIVATIVE | 第一三共株式会社 | 2015-08-27 | — | — | WO | disclosed |
| CN-100384889-C | Polymerization of olefins | DU PONT (US) | 2008-04-30 | — | — | CN | disclosed |
| EP-0952997-B1 | POLYMERIZATION OF OLEFINS | DU PONT (US) | 2004-08-11 | — | — | EP | disclosed |
| US-4385063-A | Thieno [3'2':5,6]cyclohepta [1,2-b]pyrrole derivatives | BEECHAM GROUP LIMITED (GB) | 1983-05-24 | — | — | US | disclosed |
| EP-0065324-A1 | 1,3-Diazepine compounds | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1982-11-24 | — | — | EP | disclosed |
| US-4359423-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | BEECHAM GROUP LIMITED (GB) | 1982-11-16 | — | — | US | disclosed |
| EP-0049999-A2 | Cyclic compounds and their preparation and use | BEECHAM GROUP PLC (GB) | 1982-04-21 | — | — | EP | disclosed |
| EP-0035853-A2 | Thienocycloheptapyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1981-09-16 | — | — | EP | disclosed |
| EP-0034424-A2 | Seven-membered ring compounds as inhibitors of cytidine deaminase | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1981-08-26 | — | — | EP | disclosed |
| WO-1981002164-A1 | SEVEN-MEMBERED RING COMPOUNDS AS INHIBITORS OF CYTIDINE DEAMINASE | US COMMERCE (US) | 1981-08-06 | — | — | WO | disclosed |
| EP-0032048-A1 | Pyrroloylpyrrole derivatives, processes for their preparation and their use | BEECHAM GROUP PLC (GB) | 1981-07-15 | — | — | EP | disclosed |
| US-4275057-A | CANCER AND ANTITUMOR DRUG RESEARCH | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1981-06-23 | — | — | US | disclosed |
| EP-0024807-A1 | Benzocycloheptapyrrolealkanoic acids and their derivatives, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1981-03-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078078-A1 | CONVERSION OF MUCONOLACTONE TO BETA-KETOADIPATES AND METHODS THEREFOR | PRKCD, PRKCZ, KHK | TSHR 2889/4885LMNA 4241/4885KDM4E 451/4885 |
| US-20170107207-A1 | AMINOPYRAZOLONE DERIVATIVE | ATAD5, ATP1A1, TIPRL | TSHR 3682/4885LMNA 4165/4885KDM4E 1929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.