Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12989425 | 0.83 | SIGMAR1 (0.42) | SIGMAR1CHRM5CHRM3MEN1KMT2A | |
| SCHEMBL23372759 | 0.75 | SIGMAR1 (0.40) | SIGMAR1CHRM5CHRM3MEN1KMT2A | |
| SCHEMBL23199266 | 0.74 | ALDH1A1 (0.43) | SIGMAR1CHRM5CHRM3MEN1KMT2A | |
| SCHEMBL28762420 | 0.73 | CHRM5 (0.40) | SIGMAR1CHRM5CHRM3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27945157 | 0.73 | ALDH1A1 (0.42) | SIGMAR1CHRM5CHRM3MEN1KMT2A | |
| Iodide SCHEMBL15637801 | 0.72 | SIGMAR1 (0.37) | SIGMAR1CHRM5CHRM3MEN1KMT2A | |
| SCHEMBL2220722 | 0.72 | ALDH1A1 (0.49) | SIGMAR1CHRM5CHRM3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27453248 | 0.72 | CHRM5 (0.41) | SIGMAR1CHRM5CHRM3MEN1KMT2A | |
| SCHEMBL29010574 | 0.71 | CHRM5 (0.39) | SIGMAR1CHRM5CHRM3MEN1KMT2A | |
| SCHEMBL8849859 | 0.70 | CYP4F2 (0.47) | MEN1KMT2AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521711-A1 | QUATERNARY AMMONIUM SALT PRODRUGS | Alkermes, Inc. (US) | 2012-11-14 | — | — | EP | disclosed |
| WO-2011084846-A1 | QUATERNARY AMMONIUM SALT PRODRUGS | ALKERMES, INC. (US) | 2011-07-14 | — | — | WO | disclosed |