Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12989425 | 0.77 | SIGMAR1 (0.42) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8140389 | 0.75 | SIGMAR1 (0.51) | ALDH1A1KMT2AMAPTSIGMAR1OPRD1 | |
| SCHEMBL15637079 | 0.73 | SIGMAR1 (0.47) | KMT2AMEN1SIGMAR1OPRD1 | |
| SCHEMBL28236368 | 0.72 | ALDH1A1 (0.51) | ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL25358246 | 0.72 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL2428144 | 0.72 | KMT2A (0.52) | ALDH1A1KMT2AMAPTMEN1CHRM2 | |
| SCHEMBL395978 | 0.72 | PIN1 (0.54) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| Benzene SCHEMBL28258998 | 0.72 | PIN1 (0.54) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL2221113 | 0.72 | SIGMAR1 (0.39) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL23748837 | 0.71 | KMT2A (0.50) | ALDH1A1KMT2AMAPTMEN1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521711-A1 | QUATERNARY AMMONIUM SALT PRODRUGS | Alkermes, Inc. (US) | 2012-11-14 | — | — | EP | disclosed |
| WO-2011084846-A1 | QUATERNARY AMMONIUM SALT PRODRUGS | ALKERMES, INC. (US) | 2011-07-14 | — | — | WO | disclosed |