Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 5/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | KDM4A | O75164 | 1/20 | 0.59 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.59 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.59 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19958499 | 1.00 | PAOX (0.81) | PAOXHIF1AKDM4EMAPK1KDM4A | |
| SCHEMBL1409002 | 0.90 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1KDM4A | |
| SCHEMBL19816770 | 0.90 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1KDM4A | |
| SCHEMBL346746 | 0.90 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1KDM4A | |
| SCHEMBL1408891 | 0.90 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1KDM4A | |
| SCHEMBL285321 | 0.90 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1KDM4A | |
| SCHEMBL7552315 | 0.90 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1KDM4A | |
| SCHEMBL21842271 | 0.90 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1KDM4A | |
| SCHEMBL12006469 | 0.90 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1KDM4A | |
| SCHEMBL1409041 | 0.90 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131585-B1 | MULTIDENTATE BIFUNCTIONAL CHELATING AGENTS FOR RADIONUCLIDE COMPLEXATION IN DIAGNOSTICS AND THERAPY | UNIV ZUERICH (CH) | 2020-07-15 | — | — | EP | disclosed |