Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 5/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | KDM4A | O75164 | 1/20 | 0.59 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.59 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.59 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22211260 | 1.00 | PAOX (0.81) | PAOXHIF1AKDM4EMAPK1KDM4A | |
| SCHEMBL1409002 | 0.90 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1KDM4A | |
| SCHEMBL19816770 | 0.90 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1KDM4A | |
| SCHEMBL346746 | 0.90 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1KDM4A | |
| SCHEMBL1408891 | 0.90 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1KDM4A | |
| SCHEMBL285321 | 0.90 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1KDM4A | |
| SCHEMBL7552315 | 0.90 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1KDM4A | |
| SCHEMBL21842271 | 0.90 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1KDM4A | |
| SCHEMBL12006469 | 0.90 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1KDM4A | |
| SCHEMBL1409041 | 0.90 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983020-B1 | AGENTS FOR CLEAVING LABELS FROM BIOMOLECULES IN VIVO | TAGWORKS PHARMACEUTICALS B V (NL) | 2024-06-26 | — | — | EP | disclosed |
| US-20180071265-A1 | Method of Treating or Preventing Pathologic Effects of Acute Increases in Hyperglycemia and/or Acute Increases of Free Fatty Acid Flux | GURTNER, GEOFFREY C. | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180071265-A1 | Method of Treating or Preventing Pathologic Effects of Acute Increases in Hyperglycemia and/or Acute Increases of Free Fatty Acid Flux | ATF4, NOX4, ATF1 | PAOX 203/4885HIF1A 311/4885KDM4E 4326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.