Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 10/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4808147 | 0.86 | ADAM17 (0.47) | ADAM17TACR1TACR3SMN1; SMN2 | |
| SCHEMBL4805340 | 0.76 | POLB (0.44) | ADAM17POLBNPC1RAB9ALMNA | |
| SCHEMBL4807305 | 0.74 | KDM4E (0.51) | ADAM17POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18494342 | 0.74 | MAPT (0.41) | ADAM17POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4811587 | 0.72 | ADAM17 (0.40) | ADAM17POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4817042 | 0.70 | ADAM17 (0.45) | ADAM17TACR1TACR3SMN1; SMN2 | |
| SCHEMBL4811198 | 0.70 | TDP1 (0.41) | ADAM17POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6060766 | 0.70 | HPGD (0.38) | SMN1; SMN2EPHX2LMNA | |
| SCHEMBL22211342 | 0.69 | TACR1 (0.44) | POLBTACR1TACR3NPC1RAB9A | |
| SCHEMBL9588887 | 0.68 | ADAM17 (0.40) | ADAM17POLBTACR1TACR3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3680227-A1 | METHOD FOR PREPARING SUBSTITUTED PHENYLACETIC ACID DERIVATIVE | Jiangsu Ruike Medical Science And Technology Co., Ltd. (CN) | 2020-07-15 | — | — | EP | disclosed |