Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGDS | O60760 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19928776 | 0.89 | CHRM1 (0.45) | CNR1 | |
| SCHEMBL22212609 | 0.88 | ALDH1A1 (0.46) | CNR1RAB9ANPC1CNR2ALDH1A1 | |
| SCHEMBL19932638 | 0.88 | CNR2 (0.46) | CNR1RAB9ANPC1CNR2ABHD6 | |
| Hydrochloric Acid SCHEMBL21545736 | 0.88 | CHRM1 (0.45) | CNR1 | |
| SCHEMBL22212615 | 0.83 | PARP1 (0.40) | CNR1RAB9ANPC1CNR2ABHD6 | |
| SCHEMBL22212640 | 0.83 | CHRM1 (0.51) | CNR1CNR2 | |
| SCHEMBL22212656 | 0.83 | PARP1 (0.42) | CNR1RAB9ANPC1CNR2SMN1; SMN2 | |
| SCHEMBL22212644 | 0.81 | CHRM1 (0.50) | — | |
| SCHEMBL22212653 | 0.81 | PARP1 (0.46) | CNR1RAB9ANPC1CNR2 | |
| SCHEMBL21935667 | 0.80 | SMN1; SMN2 (0.48) | EPHX2CNR1RAB9ANPC1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507289-B1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LTD (IN) | 2020-07-15 | — | — | EP | disclosed |