Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19932638 | 0.91 | CNR2 (0.46) | PARP1NPC1RAB9ACNR1CNR2 | |
| SCHEMBL19932688 | 0.89 | CHRM1 (0.43) | CNR2 | |
| Hydrochloric Acid SCHEMBL21545732 | 0.88 | CHRM1 (0.42) | CNR2 | |
| SCHEMBL22212653 | 0.88 | PARP1 (0.46) | PARP1NPC1RAB9ABRD4CNR1 | |
| SCHEMBL22212615 | 0.86 | PARP1 (0.40) | PARP1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22212609 | 0.85 | ALDH1A1 (0.46) | PARP1NPC1RAB9AALDH1A1BRD4 | |
| SCHEMBL22212636 | 0.83 | EPHX2 (0.46) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL22212644 | 0.81 | CHRM1 (0.50) | PARP1 | |
| SCHEMBL19932637 | 0.79 | CHRM1 (0.47) | — | |
| SCHEMBL22212640 | 0.79 | CHRM1 (0.51) | PARP1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507289-B1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LTD (IN) | 2020-07-15 | — | — | EP | disclosed |