Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 7/20 | 0.51 |
| ▸ | CCNC | P24863 | 3/20 | 0.47 |
| ▸ | CDK8 | P49336 | 3/20 | 0.47 |
| ▸ | AURKA | O14965 | 2/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | AXL | P30530 | 4/20 | 0.39 |
| ▸ | MERTK | Q12866 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19932686 | 0.90 | CHRM1 (0.61) | CHRM1 | |
| Hydrochloric Acid SCHEMBL21545691 | 0.89 | CHRM1 (0.61) | CHRM1 | |
| SCHEMBL22212609 | 0.84 | ALDH1A1 (0.46) | CNR1CNR2PARP1 | |
| SCHEMBL19932638 | 0.84 | CNR2 (0.46) | CNR1CNR2PARP1 | |
| SCHEMBL22212636 | 0.83 | EPHX2 (0.46) | CNR1CNR2 | |
| SCHEMBL22212615 | 0.81 | PARP1 (0.40) | CHRM1CNR1CNR2PARP1 | |
| SCHEMBL22212644 | 0.81 | CHRM1 (0.50) | CHRM1PARP1 | |
| SCHEMBL22212656 | 0.79 | PARP1 (0.42) | CNR1CNR2PARP1 | |
| SCHEMBL22212639 | 0.78 | CHRM1 (0.69) | CHRM1CCNCCDK8 | |
| SCHEMBL19932682 | 0.78 | CHRM1 (0.57) | CHRM1CCNCCDK8AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507289-B1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LTD (IN) | 2020-07-15 | — | — | EP | disclosed |