Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 5/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22212642 | 0.94 | CHRM1 (0.37) | CHRM1PDE2APDE11AALOX5AP | |
| SCHEMBL28500321 | 0.79 | CHRM1 (0.40) | CHRM1PDE2APDE11AALOX5APECE1 | |
| SCHEMBL19925995 | 0.77 | P2RX3 (0.38) | CHRM1PDE2APDE11A | |
| SCHEMBL19932659 | 0.70 | P2RX3 (0.38) | CHRM1PDE2APDE11AGRM2 | |
| SCHEMBL19932582 | 0.68 | ADORA1 (0.41) | CHRM1PDE2APDE11A | |
| SCHEMBL21545739 | 0.67 | CHRM1 (0.64) | CHRM1PDE2APDE11A | |
| SCHEMBL20030498 | 0.66 | CHRM1 (0.49) | CHRM1PDE2APDE11A | |
| SCHEMBL19260906 | 0.66 | CHRM1 (0.42) | CHRM1PDE2APDE11AALOX5APECE1 | |
| SCHEMBL20030906 | 0.66 | CHRM1 (0.42) | CHRM1PDE2APDE11AECE1 | |
| SCHEMBL19268068 | 0.64 | CHRM1 (0.44) | CHRM1PDE2APDE11AECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507289-B1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LTD (IN) | 2020-07-15 | — | — | EP | disclosed |