Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.38 |
| ▸ | PRKCI | P41743 | 3/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19925995 | 0.93 | P2RX3 (0.38) | P2RX3PRKCIMTORPARP1TNKS2 | |
| SCHEMBL19932582 | 0.90 | ADORA1 (0.41) | P2RX3PRKCIMTORPARP1TNKS2 | |
| SCHEMBL19932658 | 0.82 | CHRM1 (0.61) | MTORCHRM1PDE2APDE11A | |
| SCHEMBL28904624 | 0.82 | CHRM1 (0.61) | MTORCHRM1PDE2APDE11A | |
| SCHEMBL28500321 | 0.82 | CHRM1 (0.40) | P2RX3CHRM1PDE2APDE11AP2RX7 | |
| SCHEMBL19925934 | 0.76 | PTGER4 (0.43) | P2RX3PRKCIMTORPARP1TNKS2 | |
| SCHEMBL19932597 | 0.73 | ADORA1 (0.44) | P2RX3MTORPARP1TNKS2PARP2 | |
| SCHEMBL19932702 | 0.70 | CNR2 (0.44) | PARP1 | |
| SCHEMBL16033973 | 0.70 | P2RX7 (0.55) | PARP1TNKS2PARP2ESR2P2RX7 | |
| SCHEMBL17541257 | 0.69 | GRM2 (0.58) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507289-B1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LTD (IN) | 2020-07-15 | — | — | EP | disclosed |
| WO-2018042362-A1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LIMITED (IN) | 2018-03-08 | — | — | WO | disclosed |