Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 5/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.31 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.31 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | KDM4B | O94953 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19925995 | 0.89 | P2RX3 (0.38) | CHRM1PDE2APDE11AP2RX7P2RX3 | |
| SCHEMBL19932659 | 0.82 | P2RX3 (0.38) | CHRM1PDE2APDE11AP2RX7P2RX3 | |
| SCHEMBL19932582 | 0.82 | ADORA1 (0.41) | CHRM1PDE2APDE11AP2RX7P2RX3 | |
| SCHEMBL22212646 | 0.79 | CHRM1 (0.37) | CHRM1PDE2APDE11AECE1ALOX5AP | |
| SCHEMBL21545739 | 0.75 | CHRM1 (0.64) | CHRM1PDE2APDE11A | |
| SCHEMBL19932658 | 0.75 | CHRM1 (0.61) | CHRM1PDE2APDE11A | |
| SCHEMBL28904624 | 0.75 | CHRM1 (0.61) | CHRM1PDE2APDE11A | |
| SCHEMBL22212642 | 0.72 | CHRM1 (0.37) | CHRM1PDE2APDE11AALOX5AP | |
| SCHEMBL19925934 | 0.71 | PTGER4 (0.43) | P2RX3CNR2 | |
| SCHEMBL20030498 | 0.70 | CHRM1 (0.49) | CHRM1PDE2APDE11A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952302-B | Positive allosteric modulators of muscarinic M1 receptors | 苏文生命科学有限公司 | 2020-11-24 | — | — | CN | disclosed |