SCHEMBL22216474

SCHEMBL22216474

CC(C)(C)CN1CCC(=O)CC1=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PER2 O15055 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22323044 0.85 PER2 (0.35) PER2
SCHEMBL22323094 0.80 P2RX7 (0.33)
SCHEMBL17898499 0.79
SCHEMBL3370791 0.77 INMT (0.33)
SCHEMBL12228961 0.75 PIK3CD (0.53) PER2
SCHEMBL12032481 0.73 PER2 (0.50) PER2
SCHEMBL20762080 0.72 PER2 (0.49) PER2
SCHEMBL21401133 0.72 PER2 (0.49) PER2
SCHEMBL13508581 0.72 PER2 (0.49) PER2
SCHEMBL28177394 0.72 TSHR (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111434662-B Haloallylamine compound and application thereof 药捷安康(南京)科技股份有限公司 2023-01-10 CN disclosed
EP-3892621-A1 HALOALLYLAMINE COMPOUNDS AND APPLICATION THEREOF Nanjing Transthera Biosciences Co., Ltd. (CN) 2021-10-13 EP disclosed
WO-2020143763-A1 HALOALLYLAMINE COMPOUNDS AND APPLICATION THEREOF 南京药捷安康生物科技有限公司 2020-07-16 WO disclosed