Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | CTSD | P07339 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.60 |
| ▸ | TDO2 | P48775 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.53 |
| ▸ | WNT3A | P56704 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31337028 | 1.00 | NPC1 (0.70) | NPC1CTSDIDO1TDO2HDAC8 | |
| Anisole SCHEMBL11599826 | 0.92 | NPC1 (0.65) | NPC1CTSDIDO1TDO2HDAC8 | |
| SCHEMBL29987209 | 0.90 | NPC1 (0.83) | NPC1CTSDIDO1TDO2HDAC8 | |
| SCHEMBL21128714 | 0.90 | NPC1 (0.83) | NPC1CTSDIDO1TDO2HDAC8 | |
| SCHEMBL2723234 | 0.85 | NPC1 (0.75) | NPC1CTSDIDO1TDO2HDAC8 | |
| SCHEMBL447573 | 0.85 | NPC1 (0.70) | NPC1CTSDIDO1TDO2HDAC8 | |
| SCHEMBL3848150 | 0.84 | CTSD (0.69) | NPC1CTSDIDO1TDO2HDAC8 | |
| SCHEMBL2199445 | 0.83 | CTSD (0.62) | NPC1CTSDIDO1TDO2HDAC8 | |
| SCHEMBL10965906 | 0.83 | NPC1 (0.50) | NPC1CTSDIDO1TDO2HDAC8 | |
| SCHEMBL15979734 | 0.82 | CTNNB1 (0.71) | NPC1CTSDIDO1TDO2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060142588-A1 | Acetoacetylation of alcohols, thiols and amines in a microreactor | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2006-06-29 | — | — | US | claimed |
| CN-1745056-A | Acetoacetylation of alcohols, thiols, and amines in microreactors | CLARIANT GMBH (DE) | 2006-03-08 | — | — | CN | claimed |
| CN-116354829-B | Preparation method and application of pentyenediamine adipate | 中国科学院长春应用化学研究所 | 2025-02-07 | — | — | CN | disclosed |
| CN-116354829-A | Preparation method and application of pentyenediamine adipate | 中国科学院长春应用化学研究所 | 2023-06-30 | — | — | CN | disclosed |
| CN-109971211-A | Color compositions | 山阳色素株式会社 | 2019-07-05 | — | — | CN | disclosed |
| EP-2216312-B1 | PROCESS FOR PRODUCING ORGANIC COMPOUND | M TECHNIQUE CO LTD (JP) | 2019-05-01 | — | — | EP | disclosed |
| CN-108912723-A | Utilize the method for solid particle one pot process azo-compound | 天津大学 | 2018-11-30 | — | — | CN | disclosed |
| CN-108863834-A | A kind of new synthetic method of 2- fluoro -1,3- dicarbonyl compound | 信阳师范学院 | 2018-11-23 | — | — | CN | disclosed |
| CN-101903310-B | Method for producing organic compound | M TECH CO LTD | 2014-12-17 | — | — | CN | disclosed |
| US-8592498-B2 | Method for producing organic compound and organic compound obtained by the method | M. TECHNIQUE CO., LTD. (JP) | 2013-11-26 | — | — | US | disclosed |
| US-7989633-B2 | 4-Chromenonyl-1,4-dihydropyridines and their use | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-08-02 | — | — | US | disclosed |
| WO-2004067492-A1 | ACETOACETYLATION OF ALCOHOLS, THIOLS AND AMINES IN A MICROREACTOR | CLARIANT GMBH (DE) | 2004-08-12 | — | — | WO | disclosed |
| WO-2003051890-A1 | IMIDAZO [2,1-B]-1,3,4-THIADIAZOLE SUFLONAMIDES | AEGERA THERAPEUTICS INC. (CA) | 2003-06-26 | — | — | WO | disclosed |
| EP-0210284-B1 | 1,3-DITHIOL-2-YLIDENE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-08-19 | — | — | EP | disclosed |
| EP-0234480-A2 | 1, 3-diketone derivatives and their use | NIHON NOHYAKU CO., LTD. (JP) | 1987-09-02 | — | — | EP | disclosed |
| US-4668799-A | Anti-hepatitis and anti-cirrhotic 1,3-dithiol-2-ylidene derivatives, and pharmaceutical compositions therefor | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-05-26 | — | — | US | disclosed |
| EP-0210284-A1 | 1,3-Dithiol-2-ylidene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |
| US-4182873-A | AMINATION OF MERCAPTO THIAZOLE OR DISULFIDE | RHONE-POULENC S.A. (FR) | 1980-01-08 | — | — | US | disclosed |
| US-3985718-A | AN OXIDIZING AGENT, A CHELATE COMPOUND, AN ELECTRON DONOR AND A CHELATING COMPLEX | RHONE-POULENC S.A. (FR) | 1976-10-12 | — | — | US | disclosed |
| US-3935272-A | Process for the oxidation of olefine compounds | RHONE-POULENC S.A. (FR) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142588-A1 | Acetoacetylation of alcohols, thiols and amines in a microreactor | ADH1A, GRHPR, AKR1C2 | NPC1 3537/4885CTSD 4666/4885IDO1 2695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.