SCHEMBL2222211

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2223020	0.93	KCNH2 (0.49)	KCNH2KDM4ELMNAHTTSMN1; SMN2
	SCHEMBL2222150	0.91	KCNH2 (0.58)	KCNH2TDO2LMNAHTTSMN1; SMN2
	SCHEMBL2222673	0.89	CYP3A4 (0.43)	KCNH2KDM4ELMNAHTTSMN1; SMN2
	SCHEMBL2272640	0.89	MEN1 (0.46)	KCNH2KDM4ESMN1; SMN2CYP3A4DRD2
	SCHEMBL2226483	0.86	KCNH2 (0.47)	KCNH2TDO2CYP3A4DRD2SLC6A2
	SCHEMBL2266345	0.86	KCNH2 (0.43)	KCNH2TDO2CYP3A4DRD2HTR6
	SCHEMBL2224088	0.85	KCNH2 (0.43)	KCNH2TDO2CYP3A4DRD2SLC6A2
	SCHEMBL2221872	0.83	KCNH2 (0.42)	KCNH2TDO2CYP3A4HTR6CDK2
	SCHEMBL2222402	0.83	KCNH2 (0.60)	KCNH2LMNAHTTSMN1; SMN2CYP3A4
	SCHEMBL2221770	0.81	KCNH2 (0.49)	KCNH2KDM4ELMNAHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.