⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63687 | 0.80 | — | — | |
| SCHEMBL2568905 | 0.80 | PRKCA (0.40) | — | |
| SCHEMBL15429216 | 0.80 | PRKCA (0.40) | — | |
| SCHEMBL13589787 | 0.79 | TSHR (0.39) | — | |
| SCHEMBL122175 | 0.78 | — | — | |
| SCHEMBL17403391 | 0.77 | CYP4F2 (0.38) | — | |
| SCHEMBL23293628 | 0.76 | ALDH1A1 (0.36) | — | |
| SCHEMBL15803755 | 0.76 | CYP4F2 (0.41) | — | |
| SCHEMBL19788104 | 0.76 | — | — | |
| SCHEMBL3978142 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9551712-B2 | Volatile organic compounds as diagnostic markers for various types of cancer | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2017-01-24 | — | — | US | claimed |
| US-20120326092-A1 | VOLATILE ORGANIC COMPOUNDS AS DIAGNOSTIC MARKERS FOR VARIOUS TYPES OF CANCER | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2012-12-27 | — | — | US | claimed |
| WO-2011083473-A1 | VOLATILE ORGANIC COMPOUNDS AS DIAGNOSTIC MARKERS FOR VARIOUS TYPES OF CANCER | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2011-07-14 | — | — | WO | claimed |
| US-20240426722-A1 | Instant Non-Invasive High-Throughput Disease Screening | POSTREL RICHARD (US) | 2024-12-26 | — | — | US | disclosed |
| US-20240345021-A1 | Handheld Device for Early Detection of Disease, Biological, Chemical, and Pathogenic Agents | POSTREL RICHARD (US) | 2024-10-17 | — | — | US | disclosed |
| US-11988660-B2 | Rapid screening for infectious diseases | VOC HEALTH, INC. | 2024-05-21 | — | — | US | disclosed |
| CN-118019982-A | Diagnosis of autism spectrum disorders by multiple sets of school platforms | 耶路撒冷希伯来大学伊萨姆研发有限公司 | 2024-05-10 | — | — | CN | disclosed |
| US-20230251243-A1 | RAPID SCREENING DEVICE FOR DETECTING COVID19 AND OTHER INFECTIONS DISEASES | VOC HEALTH, INC. | 2023-08-10 | — | — | US | disclosed |
| WO-2023283031-A2 | HANDHELD DEVICE FOR EARLY DETECTION OF DISEASE, BIOLOGICAL, CHEMICAL, AND PATHOGENIC AGENTS | POSTREL RICHARD (US) | 2023-01-12 | — | — | WO | disclosed |
| US-20210286269-A1 | METHOD FOR FORMING SEMICONDUCTOR STRUCTURE | TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) | 2021-09-16 | — | — | US | disclosed |
| US-9551712-B2 | Volatile organic compounds as diagnostic markers for various types of cancer | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2017-01-24 | — | — | US | disclosed |
| US-20120326092-A1 | VOLATILE ORGANIC COMPOUNDS AS DIAGNOSTIC MARKERS FOR VARIOUS TYPES OF CANCER | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2012-12-27 | — | — | US | disclosed |
| WO-2011083473-A1 | VOLATILE ORGANIC COMPOUNDS AS DIAGNOSTIC MARKERS FOR VARIOUS TYPES OF CANCER | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2011-07-14 | — | — | WO | disclosed |