Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24099900 | 0.89 | VNN1 (0.39) | VNN1HPGDGPR183GRM5ALDH1A1 | |
| SCHEMBL21201821 | 0.85 | HPGD (0.52) | HPGDGRM5ALDH1A1TSHRRECQL | |
| SCHEMBL22226402 | 0.82 | NNMT (0.57) | VNN1HPGDNNMTCYP3A4PRMT5 | |
| SCHEMBL24463699 | 0.82 | NNMT (0.56) | VNN1HPGDGRM5NNMTPRMT5 | |
| SCHEMBL22225998 | 0.80 | HPGD (0.51) | HPGDALDH1A1TSHRRECQLNNMT | |
| SCHEMBL22226018 | 0.79 | FEN1 (0.41) | GRM5ALDH1A1GAAPIK3R1PIK3CA | |
| SCHEMBL30874429 | 0.79 | HPGD (0.47) | HPGDALDH1A1GAATSHRRECQL | |
| SCHEMBL22207531 | 0.79 | HPGD (0.47) | HPGDALDH1A1GAATSHRRECQL | |
| SCHEMBL31285104 | 0.78 | VNN1 (0.42) | VNN1HPGDGPR183ALDH1A1GAA | |
| SCHEMBL31285147 | 0.76 | VNN1 (0.41) | VNN1HPGDGPR183ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020145250-A1 | 15-PGDH INHIBITOR | 杏林製薬株式会社 | 2020-07-16 | — | — | WO | disclosed |